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• W880830350 endingPage "e1004986" @default.
• W880830350 startingPage "e1004986" @default.
• W880830350 abstract "Many pathogenic bacteria use cell–cell signaling systems involving the synthesis and perception of diffusible signal molecules to control virulence as a response to cell density or confinement to niches. Bacteria produce signals of diverse structural classes. Signal molecules of the diffusible signal factor (DSF) family are cis-2-unsaturated fatty acids. The paradigm is cis-11-methyl-2-dodecenoic acid from Xanthomonas campestris pv. campestris (Xcc), which controls virulence in this plant pathogen. Although DSF synthesis was thought to be restricted to the xanthomonads, it is now known that structurally related molecules are produced by the unrelated bacteria Burkholderia cenocepacia and Pseudomonas aeruginosa. Furthermore, signaling involving these DSF family members contributes to bacterial virulence, formation of biofilms and antibiotic tolerance in these important human pathogens. Here we review the recent advances in understanding DSF signaling and its regulatory role in different bacteria. These advances include the description of the pathway/mechanism of DSF biosynthesis, identification of novel DSF synthases and new members of the DSF family, the demonstration of a diversity of DSF sensors to include proteins with a Per-Arnt-Sim (PAS) domain and the description of some of the signal transduction mechanisms that impinge on virulence factor expression. In addition, we address the role of DSF family signals in interspecies signaling that modulates the behavior of other microorganisms. Finally, we consider a number of recently reported approaches for the control of bacterial virulence through the modulation of DSF signaling." @default.
• W880830350 created "2016-06-24" @default.
• W880830350 creator A5005396486 @default.
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• W880830350 creator A5031422226 @default.
• W880830350 creator A5050863892 @default.
• W880830350 creator A5061335694 @default.
• W880830350 date "2015-07-16" @default.
• W880830350 modified "2023-10-16" @default.
• W880830350 title "The DSF Family of Cell–Cell Signals: An Expanding Class of Bacterial Virulence Regulators" @default.
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• W880830350 cites W1837538423 @default.
• W880830350 cites W1925565273 @default.
• W880830350 cites W1927064443 @default.
• W880830350 cites W1949162259 @default.
• W880830350 cites W1970536362 @default.
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• W880830350 cites W1971608237 @default.
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• W880830350 cites W1995903337 @default.
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• W880830350 cites W2005884838 @default.
• W880830350 cites W2012101091 @default.
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• W880830350 doi "https://doi.org/10.1371/journal.ppat.1004986" @default.
• W880830350 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4504480" @default.
• W880830350 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26181439" @default.
• W880830350 hasPublicationYear "2015" @default.
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