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• W88170045 abstract "No AccessJournal of UrologyBladder/Obstruction, Exstrophy, Augmentation1 Aug 1994Prenatally Detected Posterior Urethral Valves: Is Gestational age at Detection a Predictor of Outcome? K.A.R. Hutton, D.F.M. Thomas, R.J. Arthur, H.C. Irving, and S.E.W. Smith K.A.R. HuttonK.A.R. Hutton More articles by this author , D.F.M. ThomasD.F.M. Thomas More articles by this author , R.J. ArthurR.J. Arthur More articles by this author , H.C. IrvingH.C. Irving More articles by this author , and S.E.W. SmithS.E.W. Smith More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)32684-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Between 1982 and 1992, 67 boys with posterior urethral valves were managed at our hospital, including 32 (48%) in whom the condition was detected prenatally. We examined the relationship between gestational age at detection and outcome at a median followup of 3.9 years (range 4 months to 10 years). Detection at or before 24 weeks of gestation predicted a poor outcome with 9 of 17 patients (53%) dead or in chronic renal failure at followup. Of the cases detected later in pregnancy only 1 had a poor outcome (p = 0.01). All of the cases detected after 24 weeks of gestation had had normal second trimester scans. Growth parameters for boys in the early and late detection groups were not statistically different. However, there was a significant association between renal failure and growth with 67% versus 14% having heights less than the 3rd percentile (p = 0.05). Respiratory distress at birth predicted a poor outcome, while the presence of palpable abdominal abnormalities or vesicoureteral reflux failed to predict outcome. References 1. : Emergency treatment and long-term follow-up of posterior urethral calves. Urol. Clin. N. Amer.1990; 17: 343. Google Scholar 2. : Long-term outcome of boys with posterior urethral valves. Brit. J. Urol1988; 62: 59. Google Scholar 3. : Diagnostic ante-natal et prise en charge néo-natale des valves de 1’urètre postérieur: á propos de 33 observations. Acta Urol. Belg.1990; 58: 29. Google Scholar 4. : Prognosis for patients with prenatally diagnosed posterior urethral valves. J. Urol.1992; 148: 125. Link, Google Scholar 5. : Prognostic features in infants with obstructive uropathy due to posterior urethral valves. J. Urol.1985; 133: 240. Link, Google Scholar 6. : Predictors of eventual end stage renal disease in children with posterior urethral valves. J. Urol.1986; 136: 857. Link, Google Scholar 7. : Antenatal diagnosis of posterior urethral valves. Brit. J. Urol1993; 72: 364. Crossref, Medline, Google Scholar 8. Tanner, J. M., Whitehouse, R. H. and Takaishi, M.: Standards from birth to maturity for height, weight, height velocity, and weight velocity: British children, 1965. Part II. Arch. Dis. Child., 41: 613, 1966. Google Scholar 9. : Reference ranges for serum creatinine in infants, children and adolescents. Ann. Clin. Biochem.1990; 27: 99. Google Scholar 10. : Practical Statistics for Non-Mathematical People. Newton Abbot: David & Charles1971: 292. Google Scholar 11. : Posterior urethral valves in the British Isles: a multicenter B.A.P.S. review. J. Ped. Surg.1983; 18: 70. Google Scholar 12. : Congenital valves in the posterior urethra. Brit. Med. J.1954; 1: 623. Crossref, Medline, Google Scholar 13. : The management of posterior urethral valves by initial vesicostomy and delayed valve ablation. J. Urol.1990; 144: 1212. Link, Google Scholar 14. : Posterior urethral valves in the newborn: treatment and functional results. J. Ped. Surg.1987; 22: 165. Google Scholar 15. : Long-term urinary continence and renal function in neonates with posterior urethral valves. J. Urol.1990; 144: 1209. Link, Google Scholar 16. : Prognosis of posterior urethral valves presenting at birth. J. Ped. Surg.1986; 21: 43. Google Scholar 17. : Protective factors in posterior urethral valves. J. Urol.1988; 140: 993. Link, Google Scholar © 1994 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited bySarhan O, Zaccaria I, Macher M, Muller F, Vuillard E, Delezoide A, Sebag G, Oury J, Aigrain Y and El-Ghoneimi A (2007) Long-Term Outcome of Prenatally Detected Posterior Urethral Valves: Single Center Study of 65 Cases Managed by Primary Valve AblationJournal of Urology, VOL. 179, NO. 1, (307-313), Online publication date: 1-Jan-2008.HOFMANN R, BECKER T, MEYER-WITTKOPF M, TEKESIN I, SIERRA F and SCHMIDT S (2018) Fetoscopic Placement of a Transurethral Stent for Intrauterine Obstructive UropathyJournal of Urology, VOL. 171, NO. 1, (384-386), Online publication date: 1-Jan-2004.GLASSBERG K (2018) THE VALVE BLADDER SYNDROME: 20 YEARS LATERJournal of Urology, VOL. 166, NO. 4, (1406-1414), Online publication date: 1-Oct-2001.PODESTÁ M, RUARTE A, GARGIULO C, MEDEL R and CASTERA R (2018) URODYNAMIC FINDINGS IN BOYS WITH POSTERIOR URETHRAL VALVES AFTER TREATMENT WITH PRIMARY VALVE ABLATION OR VESICOSTOMY AND DELAYED ABLATIONJournal of Urology, VOL. 164, NO. 1, (139-144), Online publication date: 1-Jul-2000.EL-GHONEIMI A, DESGRIPPES A, LUTON D, MACHER M, GUIBOURDENCHE J, GAREL C, MULLER F, VUILLARD E, LOTTMANN H, NESSMANN C, OURY J and AIGRAIN Y (2018) OUTCOME OF POSTERIOR URETHRAL VALVES: TO WHAT EXTENT IS IT IMPROVED BY PRENATAL DIAGNOSIS?Journal of Urology, VOL. 162, NO. 3 Part 1, (849-853), Online publication date: 1-Sep-1999.BROCK J, HUNLEY T, ADAMS M and KON V (2018) ROLE OF THE RENIN-ANGIOTENSIN SYSTEM IN DISORDERS OF THE URINARY TRACTJournal of Urology, VOL. 160, NO. 5, (1812-1819), Online publication date: 1-Nov-1998.Hutton K, Thomas D and Davies B (2018) Prenatally Detected Posterior Urethral Valves: Qualitative Assessment of Second Trimester Scans and Prediction of OutcomeJournal of Urology, VOL. 158, NO. 3, (1022-1025), Online publication date: 1-Sep-1997.Coplen D (2018) Prenatal Intervention for HydronephrosisJournal of Urology, VOL. 157, NO. 6, (2270-2277), Online publication date: 1-Jun-1997.Freedman A, Bukowski T, Smith C, Evans M, Johnson M and Gonzalez R (2018) Fetal Therapy for Obstructive Uropathy: Specific Outcomes DiagnosisJournal of Urology, VOL. 156, NO. 2S, (720-724), Online publication date: 1-Aug-1996. Volume 152Issue 2 Part 2August 1994Page: 698-701 Advertisement Copyright & Permissions© 1994 by The American Urological Association Education and Research, Inc.Keywordsgrowthprenatal diagnosischronickidney failureurethral obstructionMetricsAuthor Information K.A.R. Hutton More articles by this author D.F.M. Thomas More articles by this author R.J. Arthur More articles by this author H.C. Irving More articles by this author S.E.W. Smith More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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