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• W88393610 abstract "OBJECTIVE: To assess patient selection biases for drip and ship thrombolysis compared to those treated at our stroke center (direct presenters). BACKGROUND: The drip and ship model is a method to deliver thrombolysis to acute stroke patients in facilities lacking onsite neurology coverage. To date, no study has examined if there are biases in how patients are selected for this treatment. DESIGN/METHODS: We retrospectively reviewed consecutive patients who received thrombolysis at an outside facility with subsequent transfer to our stroke center between 2009 and 2011. Patients received thrombolysis after telephone consultation with a stroke specialist. We examined demographics, vascular risk factors, laboratory values, stroke severity and short term outcomes including risk of symptomatic intracerebral hemorrhage (sICH). RESULTS: Ninety-six patients were identified who received thrombolysis by drip and ship: median NIHSS 9 (IQR 4, 15) vs 8 (IQR 5, 14) in direct presenters (p=0.368). The two groups did not differ with respect to gender, ethnicity, vascular risk factors, admission glucose, or smoking history. The drip and ship median age was 63 (IQR: 50, 75) compared to 68 (IQR: 55, 82) in direct presenters (p 80 was 0.31 (CI 0.15-0.61, p CONCLUSIONS: Our study showed a smaller proportion of Blacks and elderly in the drip and ship population compared to direct presenters. This may be due to a failure to present within a treatment window or may represent a bias in patient selection for transfer to a higher level of care. Disclosure: Dr. Lyerly has nothing to disclose. Dr. Albright has received research support from The Agency for Healthcare Research and Quality (AHRQ) and The National Institute on Minority Health and Health Disparities (NIMHD), National Institutes of Health. Dr. Boehme has nothing to disclose. Dr. Bavarsad Shahripour has nothing to disclose. Dr. Houston has nothing to disclose. Dr. Rawal has nothing to disclose. Dr. Kapoor has nothing to disclose. Dr. Alvi has nothing to disclose. Dr. Sisson has nothing to disclose. Dr. Alexandrov has nothing to disclose. Dr. Alexandrov has received personal compensation for activities with Genentech. Dr. Alexandrov has received personal compensation in an editorial capacity for Genentech. Dr. Alexandrov holds stock and/or stock options in Genentech, which sponsored research in which Dr. Alexandrov was involved as an investigator. Dr. Alexandrov holds stock and/or stock options in Genentech. Dr. Alexandrov has received research support from Genentech." @default.
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• W88393610 date "2013-02-12" @default.
• W88393610 modified "2023-09-26" @default.
• W88393610 title "Potential Biases in Patients Selected for Drip and Ship Thrombolysis (P04.053)" @default.
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