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- W8846 abstract "Arterial hypertension is accompanied mainly by trophic alterations in the structure of the arterial wall, such as changes in media thickness, increased collagen, loss of elastin and intimal proliferation. These changes are the result of phenotypic alterations in the smooth muscle cells. They are regulated by hemodynamic signals, blood and interstitial-borne signals, and signals from the endothelial cells. They produce alterations in the intracellular second messenger systems, and these transmit the information required to modify gene expression and thus the cell phenotype." @default.
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- W8846 date "1993-01-01" @default.
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- W8846 title "Signals regulating arterial contractile function and growth in hypertension" @default.
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- W8846 doi "https://doi.org/10.1007/978-94-011-0900-0_7" @default.
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