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- W885576296 abstract "The intention of this study was the investigation of pentraxin 3 (PTX3) in blood of people with liver disease. Former studies had already shown that PTX3 can be useful as a rapidly available marker in the pathogenesis of several inflammatory diseases. In this clinical study the PTX3 levels of 25 persons before liver transplantation were compared to 39 persons after a liver transplantation. The measurements were made with the “Quantikine® Human Pentraxin 3/TSG-14 Immunoassay“. Furthermore the people after liver transplantation were divided in the two categories three or more months after liver transplantation and five or more months after liver transplantation. The measurements of people without liver transplantion showed a high significant difference to the norm level of 2.0 ng/ml. Age and sex of the people had only little influence on the PTX3 level and could be neglected. Three or more months after liver transplantation the PTX3 levels approached to the norm, especially the measurements five or more months after liver transplantation had no significant difference to the normal range. Furthermore the measurements of PTX3 were compared to other diagnostical markers. Confronted with CRP, ALT, AST, AP and GGT there were significant and high significant differences with more explicit increases of the PTX3 levels. So you can conclude that PTX3 can be useful as a clinical marker for liver disease." @default.
- W885576296 created "2016-06-24" @default.
- W885576296 creator A5055220021 @default.
- W885576296 date "2022-02-20" @default.
- W885576296 modified "2023-09-27" @default.
- W885576296 title "Bestimmung von Pentraxin-3 im Blutserum und dessen Bedeutung für Lebererkrankungen" @default.
- W885576296 doi "https://doi.org/10.53846/goediss-3752" @default.
- W885576296 hasPublicationYear "2022" @default.
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