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- W88916635 abstract "Sonodynamic chemotherapy or sonodynamic therapy has shown potential in the management of malignant tumors. Emerging evidence has demonstrated that curcumin, isolated from a traditional Chinese herb Curcuma longa, has significant cytotoxicity and apoptotic induction upon ultrasound sonication. Flow cytometer analysis showed that ultrasound treatment in the presence of curcumin increased the level of intracellular reactive oxygen species and caused mitochondrial damage in cancer cells. Recently, our transmission electron microscopy observed more mitophagies in nasopharyngeal cancer cells treated by ultrasound sonication in the presence of curcumin, indicating mitophagy induction is an indispensable event in the mechanism of sonodynamic chemotherapy with curcumin on nasopharyngeal cancer." @default.
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- W88916635 date "2014-01-01" @default.
- W88916635 modified "2023-09-26" @default.
- W88916635 title "Mitophagy Induction and Curcumin-Mediated Sonodynamic Chemotherapy" @default.
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- W88916635 doi "https://doi.org/10.1016/b978-0-12-405528-5.00006-7" @default.
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