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- W89221575 abstract "This chapter reviews biological markers of separation induced depression in nonhuman primates and other animals. Disruption of attachment bonds, whether in humans or nonhumans, has by now been established as a very stressful event. The behavioral effects of either maternal separation or peer separation are striking and resemble the depressions shown by some humans undergoing major separations. In addition to the behavioral effects of separation, there are a variety of neurobiological consequences including effects on sleep, heart rate, body temperature, steroids, brain self-stimulation rates, brain serotonin levels, catecholamine synthesizing enzymes in the adrenal gland, and CSF norepinephrine, 5-hydroxyindoleacetic acid, homovanillic acid. These studies are summarized in this chapter. The separation response in monkeys and several other animals is influenced by a variety of pharmacological manipulations. The drugs which have been tried thus far and their main effects are dicussed in the final section of this chapter." @default.
- W89221575 created "2016-06-24" @default.
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- W89221575 date "1982-01-01" @default.
- W89221575 modified "2023-09-27" @default.
- W89221575 title "BIOLOGICAL MARKERS OF SEPARATION INDUCED DEPRESSION IN PRIMATE MODELS" @default.
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- W89221575 doi "https://doi.org/10.1016/b978-0-08-027987-9.50008-1" @default.
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