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- W89272259 abstract "Presently many laboratories are involved in studies on the regulation of the biosynthesis of proteins at the level of translation [1,2]. We have reported previously that membrane mediated events are involved in the regulation of biosynthesis of proteins [3]. Several physiological conditions (hyperosmolarity of the growth medium, hypertonic salt, DMSO, ethanol) induce a rapid increase in the number of 80S ribosomes and a concomitant decrease in the size and number of polysomes indicating that protein synthesis is affected at the level of initiation [4,5,6]. The quantitative decrease in the amount of protein synthesis is accompanied by an extensive alteration in the pattern of protein synthesis as observed upon pulse labeling of treated and untreated cells with radioactive amino acids.KeywordsErythroid DifferentiationCellular mRNAsFrog VirusFriend VirusErythroleukemia Cell LineThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
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- W89272259 date "1979-01-01" @default.
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- W89272259 title "Alterations in Translational Control Mechanisms in Friend Erythroleukemic Cells During DMSO Induced Differentiation" @default.
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- W89272259 doi "https://doi.org/10.1007/978-3-642-67057-2_37" @default.
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