Matches in SemOpenAlex for { <https://semopenalex.org/work/W89873376> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W89873376 endingPage "1768" @default.
- W89873376 startingPage "1766" @default.
- W89873376 abstract "Mechanical loading is critical for maintaining bone mass, while weightlessness, such as that associated with reduced physical activity in old age, long-term bed rest, or space flight, invariably leads to bone loss. Fragile bone tissue is more susceptible to fractures. By contrast, extremely low-level oscillatory accelerations, applied without constraint, can increase bone formation. To examine the role of vibration in preventing and improving the fragility of bone, we tested the effect of vibration on bone structure in a tail-suspended hindlimb-unloaded (HS) mouse model. Male 22-week-old Jcl-ICR mice were allocated randomly to the following groups: daily-standing control, HS without vibration, HS with vibration at 45 Hz (HS+45Hz), and HS with standing (as an alternative to vibration) (HS+stand). Vibration was given for 5 min/day for 4 weeks. During vibration, a group of mice was placed in a box on top of the vibrating device. The amplitude of vibration was 1.0 mm. After 4 weeks of treatment, the mice were anesthetized and killed by cervical dislocation. Trabecular bone of proximal tibial metaphyseal region of tibial diaphyseal region parameters were analyzed morphologically using in vivo micro-computed tomography. In trabecular bone, the microstructural parameters were improved in HS+45Hz group compared with HS and HS+stand group, including bone volume (BV/TV), trabecular thickness (Tb.Th), trabecular separation (Tb.Sp) and trabecular bone pattern factor (TBPf). In conclusion, the results suggest a beneficial effect of vibration in preserving the complexity of trabecular bone." @default.
- W89873376 created "2016-06-24" @default.
- W89873376 creator A5003684363 @default.
- W89873376 creator A5014563734 @default.
- W89873376 creator A5040911491 @default.
- W89873376 creator A5069739590 @default.
- W89873376 date "2009-01-01" @default.
- W89873376 modified "2023-09-23" @default.
- W89873376 title "Mechanical Vibration Applied in the Absence of Weight Bearing Suggest Improved Fragile Bone" @default.
- W89873376 cites W1992567157 @default.
- W89873376 cites W1996930702 @default.
- W89873376 cites W2004666994 @default.
- W89873376 cites W2046380595 @default.
- W89873376 cites W2088639621 @default.
- W89873376 cites W2096550707 @default.
- W89873376 cites W2117135793 @default.
- W89873376 cites W2167665629 @default.
- W89873376 cites W2171705946 @default.
- W89873376 doi "https://doi.org/10.1007/978-3-540-92841-6_438" @default.
- W89873376 hasPublicationYear "2009" @default.
- W89873376 type Work @default.
- W89873376 sameAs 89873376 @default.
- W89873376 citedByCount "1" @default.
- W89873376 countsByYear W898733762014 @default.
- W89873376 crossrefType "book-chapter" @default.
- W89873376 hasAuthorship W89873376A5003684363 @default.
- W89873376 hasAuthorship W89873376A5014563734 @default.
- W89873376 hasAuthorship W89873376A5040911491 @default.
- W89873376 hasAuthorship W89873376A5069739590 @default.
- W89873376 hasConcept C105702510 @default.
- W89873376 hasConcept C121332964 @default.
- W89873376 hasConcept C134018914 @default.
- W89873376 hasConcept C141071460 @default.
- W89873376 hasConcept C170700871 @default.
- W89873376 hasConcept C185592680 @default.
- W89873376 hasConcept C192562407 @default.
- W89873376 hasConcept C198394728 @default.
- W89873376 hasConcept C2776541429 @default.
- W89873376 hasConcept C2780204347 @default.
- W89873376 hasConcept C2984739757 @default.
- W89873376 hasConcept C3018268312 @default.
- W89873376 hasConcept C62520636 @default.
- W89873376 hasConcept C71924100 @default.
- W89873376 hasConceptScore W89873376C105702510 @default.
- W89873376 hasConceptScore W89873376C121332964 @default.
- W89873376 hasConceptScore W89873376C134018914 @default.
- W89873376 hasConceptScore W89873376C141071460 @default.
- W89873376 hasConceptScore W89873376C170700871 @default.
- W89873376 hasConceptScore W89873376C185592680 @default.
- W89873376 hasConceptScore W89873376C192562407 @default.
- W89873376 hasConceptScore W89873376C198394728 @default.
- W89873376 hasConceptScore W89873376C2776541429 @default.
- W89873376 hasConceptScore W89873376C2780204347 @default.
- W89873376 hasConceptScore W89873376C2984739757 @default.
- W89873376 hasConceptScore W89873376C3018268312 @default.
- W89873376 hasConceptScore W89873376C62520636 @default.
- W89873376 hasConceptScore W89873376C71924100 @default.
- W89873376 hasLocation W898733761 @default.
- W89873376 hasOpenAccess W89873376 @default.
- W89873376 hasPrimaryLocation W898733761 @default.
- W89873376 hasRelatedWork W1964916613 @default.
- W89873376 hasRelatedWork W2039344063 @default.
- W89873376 hasRelatedWork W2108419446 @default.
- W89873376 hasRelatedWork W2108545505 @default.
- W89873376 hasRelatedWork W2108669416 @default.
- W89873376 hasRelatedWork W2187211064 @default.
- W89873376 hasRelatedWork W2391830210 @default.
- W89873376 hasRelatedWork W2899084033 @default.
- W89873376 hasRelatedWork W3009263600 @default.
- W89873376 hasRelatedWork W89873376 @default.
- W89873376 isParatext "false" @default.
- W89873376 isRetracted "false" @default.
- W89873376 magId "89873376" @default.
- W89873376 workType "book-chapter" @default.