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• W899419236 endingPage "20150057" @default.
• W899419236 startingPage "20150057" @default.
• W899419236 abstract "We compare the informational architecture of biological and random networks to identify informational features that may distinguish biological networks from random. The study presented here focuses on the Boolean network model for regulation of the cell cycle of the fission yeast Schizosaccharomyces pombe . We compare calculated values of local and global information measures for the fission yeast cell cycle to the same measures as applied to two different classes of random networks: Erdös–Rényi and scale-free. We report patterns in local information processing and storage that do indeed distinguish biological from random, associated with control nodes that regulate the function of the fission yeast cell-cycle network. Conversely, we find that integrated information, which serves as a global measure of ‘emergent’ information processing, does not differ from random for the case presented. We discuss implications for our understanding of the informational architecture of the fission yeast cell-cycle network in particular, and more generally for illuminating any distinctive physics that may be operative in life." @default.
• W899419236 created "2016-06-24" @default.
• W899419236 creator A5007602899 @default.
• W899419236 creator A5058214144 @default.
• W899419236 creator A5062418865 @default.
• W899419236 date "2016-03-13" @default.
• W899419236 modified "2023-09-23" @default.
• W899419236 title "The informational architecture of the cell" @default.
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• W899419236 doi "https://doi.org/10.1098/rsta.2015.0057" @default.
• W899419236 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26857675" @default.
• W899419236 hasPublicationYear "2016" @default.
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