Matches in SemOpenAlex for { <https://semopenalex.org/work/W90065100> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W90065100 endingPage "37" @default.
- W90065100 startingPage "729" @default.
- W90065100 abstract "This study examined the acid base disturbances in 18 adults with acute renal failure (ARF) from one of new aspects, which is lactate metabolism and pathophysiology. 10 patients (55%) of them were accompanied by lactic acidosis and 9 patients (90%) of those with lactic acidosis also had severe hepatic failure. Mortality of patients with lactic acidosis was 80%, and much higher than that of ARF (66.7%). Lactate, pyruvate, lactate-to-pyruvate ratio (L/P) were 76.7 +/- 15.66 mg/dl, 3.30 +/- 0.74 mg/dl and 19.9 +/- 1.41, respectively. All of them significantly raised, compared to values of healthy adults, patients with liver cirrhosis, chronic renal failure and diabetes mellitus. Arterial pH and HCO3- levels were 7.20 +/- 0.04 and 10.6 +/- 1.20 mEq/l. Anion gap (AG) was 30.0 +/- 3.66 mEq/l. Significant correlations of lactate with pH, HCO3-, AG and L/P were demonstrated, while correlations of lactate with BUN, CR and prothrombin time were not significantly observed. Lactic acidosis results from two mechanisms. One is lactate overproduction (e.g tissue hypoxia) and the other is lactate underutilization (e.g severe liver and/or renal failure). Whenever lactic acidosis occurred, both mechanisms were present simultaneously and continuously. Especially, the latter mechanism had a very important role on it, and seemed to decide the prognosis of the patients with lactic acidosis. Therapy of lactic acidosis was very difficult. First of all, we tried to improve the circulatory failure and severe acidemia (pH less than 7.20) not to fall into vicious cycle. Then, CAVH, if combined with alkali infusion, seemed to be the most useful technique in managing lactic acidosis with ARF." @default.
- W90065100 created "2016-06-24" @default.
- W90065100 creator A5042662419 @default.
- W90065100 creator A5084497223 @default.
- W90065100 date "1990-06-01" @default.
- W90065100 modified "2023-09-23" @default.
- W90065100 title "[Acute renal failure with lactic acidosis]." @default.
- W90065100 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2214321" @default.
- W90065100 hasPublicationYear "1990" @default.
- W90065100 type Work @default.
- W90065100 sameAs 90065100 @default.
- W90065100 citedByCount "2" @default.
- W90065100 crossrefType "journal-article" @default.
- W90065100 hasAuthorship W90065100A5042662419 @default.
- W90065100 hasAuthorship W90065100A5084497223 @default.
- W90065100 hasConcept C126322002 @default.
- W90065100 hasConcept C134018914 @default.
- W90065100 hasConcept C2775920511 @default.
- W90065100 hasConcept C2777299393 @default.
- W90065100 hasConcept C2778553927 @default.
- W90065100 hasConcept C2779246250 @default.
- W90065100 hasConcept C2780317664 @default.
- W90065100 hasConcept C523546767 @default.
- W90065100 hasConcept C54355233 @default.
- W90065100 hasConcept C71924100 @default.
- W90065100 hasConcept C86803240 @default.
- W90065100 hasConcept C90924648 @default.
- W90065100 hasConceptScore W90065100C126322002 @default.
- W90065100 hasConceptScore W90065100C134018914 @default.
- W90065100 hasConceptScore W90065100C2775920511 @default.
- W90065100 hasConceptScore W90065100C2777299393 @default.
- W90065100 hasConceptScore W90065100C2778553927 @default.
- W90065100 hasConceptScore W90065100C2779246250 @default.
- W90065100 hasConceptScore W90065100C2780317664 @default.
- W90065100 hasConceptScore W90065100C523546767 @default.
- W90065100 hasConceptScore W90065100C54355233 @default.
- W90065100 hasConceptScore W90065100C71924100 @default.
- W90065100 hasConceptScore W90065100C86803240 @default.
- W90065100 hasConceptScore W90065100C90924648 @default.
- W90065100 hasIssue "6" @default.
- W90065100 hasLocation W900651001 @default.
- W90065100 hasOpenAccess W90065100 @default.
- W90065100 hasPrimaryLocation W900651001 @default.
- W90065100 hasRelatedWork W1871937327 @default.
- W90065100 hasRelatedWork W2021963167 @default.
- W90065100 hasRelatedWork W2028135803 @default.
- W90065100 hasRelatedWork W2123000228 @default.
- W90065100 hasRelatedWork W2302115001 @default.
- W90065100 hasRelatedWork W2406765587 @default.
- W90065100 hasRelatedWork W2428326528 @default.
- W90065100 hasRelatedWork W2739369496 @default.
- W90065100 hasRelatedWork W3106259596 @default.
- W90065100 hasRelatedWork W9442893 @default.
- W90065100 hasVolume "32" @default.
- W90065100 isParatext "false" @default.
- W90065100 isRetracted "false" @default.
- W90065100 magId "90065100" @default.
- W90065100 workType "article" @default.