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- W90145731 abstract "Research on cellular function and regulation would be greatly advanced by new instrumentation using methods to alter cellular processes with spatial discrimination on the nanometer-scale. We present a novel technique for targeting submicrometer sized organelles or other biologically important regions in living cells using femtosecond laser pulses. By tightly focusing these pulses beneath the cell membrane, we can vaporize cellular material inside the cell through nonlinear optical processes. This technique enables non-invasive manipulation of the physical structure of a cell with sub-micrometer resolution. We propose to study the role mitochondria play in cell proliferation and apoptosis. Our technique provides a unique tool for the study of cell biology." @default.
- W90145731 created "2016-06-24" @default.
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- W90145731 date "2007-02-27" @default.
- W90145731 modified "2023-09-24" @default.
- W90145731 title "Using Femtosecond Laser Subcellular Surgery as a Tool to Study Cell Biology" @default.
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- W90145731 doi "https://doi.org/10.2172/1036835" @default.
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