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- W90191808 abstract "Mononuclear phagocytes form a body-wide system of cells (1) that originate from precursors in the bone marrow, circulate in the blood, and emigrate from the vascular compartment into the tissues where they spend the major portion of their life span. At the time of their emigration from the blood into the tissues mononuclear phagocytes are extremely immature cells. In the tissues they differentiate into their adult form, the macrophage. Macrophages in different tissues develop characteristic metabolic and structural properties. Thus alveolar macrophages develop a high capacity for oxidative metabolites (2), while splenic and peritoneal macrophages derive the major proportion of their metabolic energy from anerobic glycolysis (3). Inflammatory macrophages may develop into sheets of interlocking epithelioid cells, or fuse to form multinucleate giant cells (4). In the bones they fuse to produce osteoclasts (5)." @default.
- W90191808 created "2016-06-24" @default.
- W90191808 creator A5027892366 @default.
- W90191808 date "1982-01-01" @default.
- W90191808 modified "2023-09-25" @default.
- W90191808 title "Membrane Receptors and the Regulation of Mononuclear Phagocyte Effector Functions" @default.
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- W90191808 doi "https://doi.org/10.1007/978-1-4684-4394-3_2" @default.
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