Matches in SemOpenAlex for { <https://semopenalex.org/work/W906219400> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W906219400 abstract "Aim. To study the levels of pro- and anti-inflammatory cytokines in cervical secretion in females with cervical epithelial dysplasia and latent papillomavirus infection. Methods. The study included 120 females aged 20 to 40 years with cervical papillomavirus infection, who were assigned to two groups using «case-control» method. The first group included 60 females with latent disease, the second group - 60 females with mild and moderate cervical epithelial dysplasia (cervical intraepithelial neoplasia stages I and II). Cytokine levels in cervical secretion were measured by ELISA using «ProCon» test system. Results. ELISA test showed increased levels of interleukin-4 and interleukin-10 (43 [21; 74] and 48 [12; 88] pg/ml, respectively) and decreased levels of interleukin-2 (18.5 [5.5; 27.5] pg/ml), interleukin-6 (0.6 [0.06; 0.9] pg/ml), tumor necrosis factor alpha (88.5 [0; 123] pg/ml), interferon γ (2 [0; 4] pg/ml) in cervical secretion of females with cervical epithelial dysplasia compared to females with latent papillomavirus infection. Thus, females with cervical epithelial dysplasia showed increased levels of anti-inflammatory cytokines: interleukin-4 - by 2.7 times and interleukin-10 - by 2.4 times compared to females with latent disease, while levels of pro-inflammatory cytokines was decreased as following: interleukin-2 - by 1.4 times, interleukin-6 - by 4.5 times, tumor necrosis factor alpha - by 1.8 times, interferon γ - by 6.3 times (p 0.05). Conclusion. Imbalance of immune response cytokine regulation with anti-inflammatory cytokines prevailing might be an important factor facilitating persistence of papillomavirus in cervical epithelium and contributing to cervical epithelial dysplasia onset and progression." @default.
- W906219400 created "2016-06-24" @default.
- W906219400 creator A5083971227 @default.
- W906219400 date "2014-10-15" @default.
- W906219400 modified "2023-09-24" @default.
- W906219400 title "Cytokine profile of cervical mucus at different forms of papillomavirus infection" @default.
- W906219400 doi "https://doi.org/10.17816/kmj2207" @default.
- W906219400 hasPublicationYear "2014" @default.
- W906219400 type Work @default.
- W906219400 sameAs 906219400 @default.
- W906219400 citedByCount "0" @default.
- W906219400 crossrefType "journal-article" @default.
- W906219400 hasAuthorship W906219400A5083971227 @default.
- W906219400 hasBestOaLocation W9062194001 @default.
- W906219400 hasConcept C11988809 @default.
- W906219400 hasConcept C121608353 @default.
- W906219400 hasConcept C126322002 @default.
- W906219400 hasConcept C17991360 @default.
- W906219400 hasConcept C203014093 @default.
- W906219400 hasConcept C2775894508 @default.
- W906219400 hasConcept C2777343196 @default.
- W906219400 hasConcept C2778220009 @default.
- W906219400 hasConcept C2778690821 @default.
- W906219400 hasConcept C71924100 @default.
- W906219400 hasConcept C74172505 @default.
- W906219400 hasConcept C90924648 @default.
- W906219400 hasConceptScore W906219400C11988809 @default.
- W906219400 hasConceptScore W906219400C121608353 @default.
- W906219400 hasConceptScore W906219400C126322002 @default.
- W906219400 hasConceptScore W906219400C17991360 @default.
- W906219400 hasConceptScore W906219400C203014093 @default.
- W906219400 hasConceptScore W906219400C2775894508 @default.
- W906219400 hasConceptScore W906219400C2777343196 @default.
- W906219400 hasConceptScore W906219400C2778220009 @default.
- W906219400 hasConceptScore W906219400C2778690821 @default.
- W906219400 hasConceptScore W906219400C71924100 @default.
- W906219400 hasConceptScore W906219400C74172505 @default.
- W906219400 hasConceptScore W906219400C90924648 @default.
- W906219400 hasLocation W9062194001 @default.
- W906219400 hasOpenAccess W906219400 @default.
- W906219400 hasPrimaryLocation W9062194001 @default.
- W906219400 hasRelatedWork W2000070416 @default.
- W906219400 hasRelatedWork W2007619928 @default.
- W906219400 hasRelatedWork W2008709212 @default.
- W906219400 hasRelatedWork W2030982530 @default.
- W906219400 hasRelatedWork W2052005806 @default.
- W906219400 hasRelatedWork W2081426216 @default.
- W906219400 hasRelatedWork W2094660628 @default.
- W906219400 hasRelatedWork W2141670332 @default.
- W906219400 hasRelatedWork W2156689651 @default.
- W906219400 hasRelatedWork W2160432547 @default.
- W906219400 hasRelatedWork W2238033536 @default.
- W906219400 hasRelatedWork W2289643138 @default.
- W906219400 hasRelatedWork W2361240926 @default.
- W906219400 hasRelatedWork W2371185984 @default.
- W906219400 hasRelatedWork W2409020198 @default.
- W906219400 hasRelatedWork W2603870486 @default.
- W906219400 hasRelatedWork W2751152927 @default.
- W906219400 hasRelatedWork W2767008726 @default.
- W906219400 hasRelatedWork W2946570622 @default.
- W906219400 hasRelatedWork W3063676912 @default.
- W906219400 isParatext "false" @default.
- W906219400 isRetracted "false" @default.
- W906219400 magId "906219400" @default.
- W906219400 workType "article" @default.