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- W90740725 abstract "The widely used plasticizer and rodent carcinogen di-(2-ethylhexyl) phthalate (DEHP) was examined for activity in the C3H 10T 1 2 murine fibroblast cell transformation system. Treatment with DEHP or its metabolite, mono-(2-ethylhexyl) phthalate, did not produce oncogenic transformation, initiate the process of transformation in cultures treated with a tumour promoter or promote the process of transformation in cultures pretreated with a chemical carcinogen. These findings are consistent with the suggestion that the carcinogenicity of DEHP is mediated by an indirect mechanism and not by covalent interaction of DEHP with DNA." @default.
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- W90740725 date "1987-01-01" @default.
- W90740725 modified "2023-09-23" @default.
- W90740725 title "Lack of di-(2-ethylhexyl) phthalate activity in the cell transformation system" @default.
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- W90740725 doi "https://doi.org/10.1016/0887-2333(87)90038-5" @default.
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