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- W90810610 abstract "Since the recognition in 1968 that the superoxide free radical, $$0_2^{bar bullet } $$ , could be produced by biological reactions (1), the radical has been implicated to play important roles in three pathophysiological processes: oxygen toxicity, inflammation, and post-ischemic tissue injury. The involvement of superoxide in oxygen toxicity has been elucidated by a great variety of studies involving both microbial and mammalian systems. This area has been well reviewed (2,3) and will not be further addressed in the present discussion. The major role of superoxide in the inflammatory process has recently become more clearly understood (4), while the involvement of superoxide in post-ischemic tissue injury is just beginning to unfold (5). What follows will describe our current concepts concerning the roles of superoxide in inflammation and ischemia." @default.
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- W90810610 date "1982-01-01" @default.
- W90810610 modified "2023-09-26" @default.
- W90810610 title "Roles of Superoxide in Inflammation and Ischemic Shock" @default.
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- W90810610 doi "https://doi.org/10.1007/978-1-4612-5829-2_25" @default.
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