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- W908755649 abstract "目的研究腰麻-硬膜外联合麻醉(CSEA)对剖宫产母婴肾素-血管紧张素-醛固酮系统(RAAS)的影响.方法将60例ASA Ⅰ级行择期剖宫产的健康产妇随机分为硬膜外麻醉组(EA组,n=30)和CSEA组(n=30).分别于注射局麻药前(T0)、切皮后即刻(T1)、胎儿娩出后即刻(T2)、术毕即刻(T3)和术后24 h(T4)取母体静脉血和胎儿娩出后胎儿脐动、静脉血测定血清肾素活性(PRA)、血管紧张素Ⅱ(AT-Ⅱ)和醛固酮(ALD)浓度;评定麻醉效果,记录痛觉阻滞平面达T7水平的时间,注射局麻药至胎儿娩出时间(Ⅰ-DI)及新生儿娩出1 min、5 min的Apgar评分.结果两组术中SP、DP、HR、SpO2的变化及新生儿娩出1 min、5 min的Apgar评分差异无显著性(P＞0.05).同EA组相比,CSEA组麻醉起效时间明显缩短,Ⅰ-DI亦明显缩短(P＜0.01).两组母体于T1、T2、T4的PRA、AT-Ⅱ、ALD值均比T0、T3值明显降低(P＜0.01),胎儿脐动、静脉血中三者值差异不明显,但明显低于母体T0、T3值(P＜0.01).结论CSEA用于剖宫产手术时,只要运用得当,不会对母婴RAAS产生不良影响." @default.
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- W908755649 date "2003-01-01" @default.
- W908755649 modified "2023-09-23" @default.
- W908755649 title "腰麻—硬膜外联合麻醉对剖宫产母婴肾素—血管紧张素—醛固酮系统的影响" @default.
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