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- W909023569 abstract "Objective: To investigate the effect of the herbal compound (NiaoSuanLiXian) on the expression of Vascular cell adhesion molecule (VCAM-1) in vascular endothelial cells. Methods: Cultured the vascular endothelial cells, and stimulated with urate(1070μmol/L). At the same time, the cells were co-incubated with the serum including medicine. The expression of VCAM-1 in the vascular endothelial cells was detected by FCM and RT-PCR. Results: The expression of VCAM-1 in the vascular endothelial cells induced by urate increased significantly than that in the control cells. 2.5%, 5%, 10% of the serum including NiaoSuanLiXian could all significantly down-regulate the expression of VCAM-1 on levels of mRNA. Conclusion: Down-regulating the expression of VCAM-1 in vascular endothelial cells induced by urate is the One of mechanism of NiaoSuanLiXian reducing the inflammatory injure." @default.
- W909023569 created "2016-06-24" @default.
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- W909023569 date "2007-01-10" @default.
- W909023569 modified "2023-09-23" @default.
- W909023569 title "尿酸利仙含药血清对尿酸盐诱导的人血管内皮细胞VCAM-1 mRNA表达的影响" @default.
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