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- W9113744 abstract "To observe the effect of electroacupuncture (EA) stimulation of Zusanli (ST 36) on intercellular adhesion molecule-1 (ICAM-1) mRNA expression and mast cell (MC) distribution in the stimulated subcutaneous tissues in nor- mal rats, so as to study the correlation between ICAM-1 mRNA expression and MC activity during EA.Twenty Wistar rats were randomly assigned to normal group and EA group. EA(2 Hz/15 Hz, 0. 1 mA) stimulation was applied to the bilateral Zusanli (ST 36) for 25 min. The expression of OICAM-1 mRNA in subcutaneous tissues of the left Zusanli (ST 36) area was detected by in situ hybridization, and MC activity of the same tissues was observed under microscope after staining with acetylcho- line esterase (AChE) and toluidine blue (TB, counterstaining), respectively.Compared with the normal group, the ICAM-1 mRNA expressed at a markedly higher level in the subcutaneous tissues of the Zusanli (ST 36) region in the EA group (P<0. 01), and MC counts were also significantly increased in the EA group (P<0. 01).EA stimulation up-regulates the expression of ICAM-1 mRNA and enhances MC release from the stimulated regional subcutaneous tissue in healthy rats, suggesting ICAM-1 played an important role in affecting the movement and recruitment of MCs towards acupoint during EA." @default.
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- W9113744 date "2014-12-01" @default.
- W9113744 modified "2023-10-18" @default.
- W9113744 title "[Effects of electroacupuncture stimulation of Zusanli (ST 36) on the regional vascular intercellular Adhesion Molecule-1 mRNA expression and mast cell activity in normal rats]." @default.
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