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- W91284606 abstract "Acetone crude extracts of Phyllanthus amarus and Tamarindus indica, acetone/methanol crude extracts of Cleome viscosa and crude extracts-Poly(ethylene glycol)ointment formulation of the plants were screened for antibacterial activity on clinical isolates; Pseudomonas aeruginosa and Staphylococcus aureus which are associated with wound infection.Crude extracts of Phyllanthus amarus and its formulation showed no inhibition on both bacteria. Crude extracts of Tamarindus indica showed potency against Pseudomonas aeruginosa at varying concentrations and was dose dependent recording a maximum zone of inhibition of 12 ± 0.15 mm at 200 mg L-1 and zone of inhibition of 6 ± 0.25 mm at 25 mg L-1 but its formulation was not potent against both bacteria. Crude extracts of Cleome viscosa was potent against P. aeruginosa but was not significantly dose dependent at 95% confidence level with zone of inhibition of 8 ± 0.35 mm at 200 mg L-1 and 25 mg L-1 concentrations of the crude extracts. Its formulation showed an increased potency against P. aeruginosa that was highly significant with maximum zone of inhibition 14 ± 0.50 mm at 100 mg g-1 of Cleome viscosa crude extracts-PEG ointment formulation compared with chloramphenicol (positive control) Cleome viscosa crude extract-PEG ointment has therefore emerged a novel formulation against P. aeruginosa hence signifying their potential in treating Pseudomonas infections." @default.
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- W91284606 date "2014-01-01" @default.
- W91284606 modified "2023-09-24" @default.
- W91284606 title "Evaluation of Antibacterial Potentiation of Crude Extracts of Phyllant h u s amarus , Tamarindus indica and Cleo me viscosa and Their Formulation" @default.
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