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- W91736357 abstract "Dendritic spines, the postsynaptic components of most excitatory synapses, have fascinated scientists since their discovery by Santiago Ramón y Cajal in 1888. Dendritic spines are heterogeneous in shape within the cortex and hippocampus, and these morphological differences between spines have been shown to reflect functional differences and pathological states. The number and shape of dendritic spines are variable on different timescales, ranging from seconds to days, through an actin-dependent process. Insufficient α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor activation leads to the disappearance of spines and synapses. Changes in the shape and density of dendritic spines are thought to be a structural correlate of synaptic plasticity, which may account for the persistence of memories." @default.
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- W91736357 date "2009-01-01" @default.
- W91736357 modified "2023-09-25" @default.
- W91736357 title "Glutamate Regulation of Dendritic Spine Form and Function" @default.
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- W91736357 doi "https://doi.org/10.1016/b978-008045046-9.01226-2" @default.
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