Matches in SemOpenAlex for { <https://semopenalex.org/work/W91765631> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W91765631 endingPage "478" @default.
- W91765631 startingPage "473" @default.
- W91765631 abstract "This chapter presents the molecular basis of the antioxidant function of selenium in mammals. For many decades, selenium has been known as one of the most toxic elements, causing the alkali disease or blind staggers. Selenium poisoning of life stock was caused by ingestion of seleniferous plants that accumulate selenium in the form of selenium analogs of methionine, S-methylcysteine, γ-glutamylcysteine, cystathionine, or adenosylmethionine. In 1954, however, Pinsent observed that selenium promoted growth of some bacteria. Since 1957, it has been generally accepted that selenium is an essential micronutrient also for mammals. Further, incorporation of the radioactive selenium-75 into a protein fraction that co- chromatographed with glutathione (GSH) peroxidase strongly suggested that selenium is an integral part of this enzyme. Glutathione peroxidase, discovered in 1957 by Mills, had first been described as an enzyme catalyzing the reduction of H2O2 by glutathione. GSH peroxidase is a homotetramer with a subunit molecular weight of about 21,000. Each subunit contains one selenium atom which, in its reduced state, is part of a selenocysteine residue. It remains to be investigated which of the many selenium deficiency syndromes observed in different animals and more recently also in humans is because of GSH peroxidase deficiency. Acute and severe selenium deficiency is obviously rare in humans and may require additional deficiencies to become critical." @default.
- W91765631 created "2016-06-24" @default.
- W91765631 creator A5008985143 @default.
- W91765631 date "1985-01-01" @default.
- W91765631 modified "2023-10-16" @default.
- W91765631 title "The Glutathione Peroxidase Reaction: Molecular Basis of the Antioxidant Function of Selenium in Mammals" @default.
- W91765631 cites W1484180915 @default.
- W91765631 cites W1595015475 @default.
- W91765631 cites W1802486171 @default.
- W91765631 cites W1844171880 @default.
- W91765631 cites W1963549348 @default.
- W91765631 cites W1965694067 @default.
- W91765631 cites W1966597352 @default.
- W91765631 cites W1988998244 @default.
- W91765631 cites W1989764450 @default.
- W91765631 cites W1996685093 @default.
- W91765631 cites W1999014341 @default.
- W91765631 cites W2027712360 @default.
- W91765631 cites W2060945422 @default.
- W91765631 cites W2061686638 @default.
- W91765631 cites W2065732704 @default.
- W91765631 cites W2077284729 @default.
- W91765631 cites W2080411487 @default.
- W91765631 cites W2132826785 @default.
- W91765631 cites W2315000366 @default.
- W91765631 doi "https://doi.org/10.1016/b978-0-12-152827-0.50047-5" @default.
- W91765631 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4092495" @default.
- W91765631 hasPublicationYear "1985" @default.
- W91765631 type Work @default.
- W91765631 sameAs 91765631 @default.
- W91765631 citedByCount "113" @default.
- W91765631 countsByYear W917656312012 @default.
- W91765631 countsByYear W917656312013 @default.
- W91765631 countsByYear W917656312014 @default.
- W91765631 countsByYear W917656312015 @default.
- W91765631 countsByYear W917656312016 @default.
- W91765631 countsByYear W917656312017 @default.
- W91765631 countsByYear W917656312018 @default.
- W91765631 countsByYear W917656312020 @default.
- W91765631 countsByYear W917656312021 @default.
- W91765631 countsByYear W917656312022 @default.
- W91765631 countsByYear W917656312023 @default.
- W91765631 crossrefType "book-chapter" @default.
- W91765631 hasAuthorship W91765631A5008985143 @default.
- W91765631 hasConcept C162008176 @default.
- W91765631 hasConcept C178790620 @default.
- W91765631 hasConcept C181199279 @default.
- W91765631 hasConcept C185592680 @default.
- W91765631 hasConcept C203580378 @default.
- W91765631 hasConcept C203663253 @default.
- W91765631 hasConcept C2776087148 @default.
- W91765631 hasConcept C2778004101 @default.
- W91765631 hasConcept C2778760513 @default.
- W91765631 hasConcept C2779135701 @default.
- W91765631 hasConcept C2779201268 @default.
- W91765631 hasConcept C538909803 @default.
- W91765631 hasConcept C553756173 @default.
- W91765631 hasConcept C55493867 @default.
- W91765631 hasConceptScore W91765631C162008176 @default.
- W91765631 hasConceptScore W91765631C178790620 @default.
- W91765631 hasConceptScore W91765631C181199279 @default.
- W91765631 hasConceptScore W91765631C185592680 @default.
- W91765631 hasConceptScore W91765631C203580378 @default.
- W91765631 hasConceptScore W91765631C203663253 @default.
- W91765631 hasConceptScore W91765631C2776087148 @default.
- W91765631 hasConceptScore W91765631C2778004101 @default.
- W91765631 hasConceptScore W91765631C2778760513 @default.
- W91765631 hasConceptScore W91765631C2779135701 @default.
- W91765631 hasConceptScore W91765631C2779201268 @default.
- W91765631 hasConceptScore W91765631C538909803 @default.
- W91765631 hasConceptScore W91765631C553756173 @default.
- W91765631 hasConceptScore W91765631C55493867 @default.
- W91765631 hasLocation W917656311 @default.
- W91765631 hasLocation W917656312 @default.
- W91765631 hasOpenAccess W91765631 @default.
- W91765631 hasPrimaryLocation W917656311 @default.
- W91765631 hasRelatedWork W136131483 @default.
- W91765631 hasRelatedWork W1568938174 @default.
- W91765631 hasRelatedWork W1576820761 @default.
- W91765631 hasRelatedWork W1965137017 @default.
- W91765631 hasRelatedWork W1976115068 @default.
- W91765631 hasRelatedWork W1987005612 @default.
- W91765631 hasRelatedWork W2060194897 @default.
- W91765631 hasRelatedWork W2088335918 @default.
- W91765631 hasRelatedWork W91765631 @default.
- W91765631 hasRelatedWork W2525093252 @default.
- W91765631 isParatext "false" @default.
- W91765631 isRetracted "false" @default.
- W91765631 magId "91765631" @default.
- W91765631 workType "book-chapter" @default.