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• W92000413 abstract "Knockout of the steroidogenic factor 1 (Sf1) gene in 46,XY mice causes complete adrenal failure associated with gonadal dysgenesis, undervirilization, and persistence of mullerian ducts [1]. SF1 (NR5A1, SF1/Ad4BP/FTZF1) is a member of the nuclear receptor superfamily, and it plays a crucial role in the fetal development of the adrenal gland [2] and testes [3]. Sf1 is considered to be the master regulator of the reproductive system because it regulates the expression of a wide array of genes required for testis and adrenal development and hormone synthesis [4]." @default.
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• W92000413 date "2011-01-01" @default.
• W92000413 modified "2023-10-03" @default.
• W92000413 title "Phenotypic Variation of SF1 Gene Mutations" @default.
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• W92000413 doi "https://doi.org/10.1007/978-1-4419-8002-1_16" @default.
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