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- W92012054 abstract "Ceftriaxone is a white crystalline powder that displays broad-spectrum antibiotic activity against Gram-positive and Gram-negative bacteria. In this article, the authors review the antibacterial mechanism of action and pharmacokinetics of ceftriaxone. They also review a novel mechanism of action of ceftriaxone, the enhancement of cellular glutamate uptake through activation of the astrocytic glutamate transporter subtype 1 (GLT-1) protein, and discuss the potential utility of ceftriaxone as a central nervous system (CNS)-active therapeutic for the treatment of diseases that lack safe and efficacious medications." @default.
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- W92012054 date "2014-01-01" @default.
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- W92012054 title "Antibiotics, β-Lactam" @default.
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- W92012054 doi "https://doi.org/10.1016/b978-0-12-385157-4.00250-5" @default.
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