Matches in SemOpenAlex for { <https://semopenalex.org/work/W92013284> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W92013284 endingPage "30" @default.
- W92013284 startingPage "225" @default.
- W92013284 abstract "Autooxidation of polyunsaturated fatty acids (PUFAs) of edible oils results in the formation of fatty acid hydroperoxides that can undergo further chemical transformations to yield a variety of re-arranged and chain-cleavage products. Since the oxidation products of PUFAs have been reported to have cytotoxic and mutagenic effects, the consumption of rancid oils and fats represents a possible health hazard for the population. Storage of corn oil at room temperature and in the refrigerator for a forty-eight month period resulted in two different qualities of oil samples, which were characterized by UV, titrimetric (peroxide value, acid value) and GC-MS methods. Earlier it was demonstrated that the increase of expression of certain oncogenes and tumor suppressor genes is a method of choice for the early detection of carcinogen exposure. Treatment of CBA/Calpha inbred mice with the two oil samples showed significantly increased expression of the Ha-ras gene in all the investigated organs (liver, lung, kidney, thymus and spleen) of the rancid corn oil-treated animals. Expression of the c-myc and the p53 genes was also increased after the rancid corn oil-treatment in all the organs but the thymus of the mice. The results suggest that rancid oils, rich in omega-6 unsaturated fatty acids, could be involved not only in tumor promotion but in initiation as well." @default.
- W92013284 created "2016-06-24" @default.
- W92013284 creator A5008866614 @default.
- W92013284 creator A5062344143 @default.
- W92013284 creator A5080825002 @default.
- W92013284 creator A5088358470 @default.
- W92013284 date "2002-05-23" @default.
- W92013284 modified "2023-09-23" @default.
- W92013284 title "Effect of rancid corn oil on some onco/suppressor gene expressions in vivo. A short-term study." @default.
- W92013284 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12017293" @default.
- W92013284 hasPublicationYear "2002" @default.
- W92013284 type Work @default.
- W92013284 sameAs 92013284 @default.
- W92013284 citedByCount "4" @default.
- W92013284 countsByYear W920132842015 @default.
- W92013284 countsByYear W920132842022 @default.
- W92013284 crossrefType "journal-article" @default.
- W92013284 hasAuthorship W92013284A5008866614 @default.
- W92013284 hasAuthorship W92013284A5062344143 @default.
- W92013284 hasAuthorship W92013284A5080825002 @default.
- W92013284 hasAuthorship W92013284A5088358470 @default.
- W92013284 hasConcept C114246631 @default.
- W92013284 hasConcept C150903083 @default.
- W92013284 hasConcept C185592680 @default.
- W92013284 hasConcept C19038510 @default.
- W92013284 hasConcept C203014093 @default.
- W92013284 hasConcept C207001950 @default.
- W92013284 hasConcept C2778206080 @default.
- W92013284 hasConcept C2780931953 @default.
- W92013284 hasConcept C2781294611 @default.
- W92013284 hasConcept C2908647359 @default.
- W92013284 hasConcept C31903555 @default.
- W92013284 hasConcept C543025807 @default.
- W92013284 hasConcept C55493867 @default.
- W92013284 hasConcept C71924100 @default.
- W92013284 hasConcept C86803240 @default.
- W92013284 hasConcept C99454951 @default.
- W92013284 hasConceptScore W92013284C114246631 @default.
- W92013284 hasConceptScore W92013284C150903083 @default.
- W92013284 hasConceptScore W92013284C185592680 @default.
- W92013284 hasConceptScore W92013284C19038510 @default.
- W92013284 hasConceptScore W92013284C203014093 @default.
- W92013284 hasConceptScore W92013284C207001950 @default.
- W92013284 hasConceptScore W92013284C2778206080 @default.
- W92013284 hasConceptScore W92013284C2780931953 @default.
- W92013284 hasConceptScore W92013284C2781294611 @default.
- W92013284 hasConceptScore W92013284C2908647359 @default.
- W92013284 hasConceptScore W92013284C31903555 @default.
- W92013284 hasConceptScore W92013284C543025807 @default.
- W92013284 hasConceptScore W92013284C55493867 @default.
- W92013284 hasConceptScore W92013284C71924100 @default.
- W92013284 hasConceptScore W92013284C86803240 @default.
- W92013284 hasConceptScore W92013284C99454951 @default.
- W92013284 hasIssue "1A" @default.
- W92013284 hasLocation W920132841 @default.
- W92013284 hasOpenAccess W92013284 @default.
- W92013284 hasPrimaryLocation W920132841 @default.
- W92013284 hasRelatedWork W1916489058 @default.
- W92013284 hasRelatedWork W1964361614 @default.
- W92013284 hasRelatedWork W1967764591 @default.
- W92013284 hasRelatedWork W2032887260 @default.
- W92013284 hasRelatedWork W2103717201 @default.
- W92013284 hasRelatedWork W2276167379 @default.
- W92013284 hasRelatedWork W2558541883 @default.
- W92013284 hasRelatedWork W3122092885 @default.
- W92013284 hasRelatedWork W772388149 @default.
- W92013284 hasRelatedWork W2189737620 @default.
- W92013284 hasVolume "22" @default.
- W92013284 isParatext "false" @default.
- W92013284 isRetracted "false" @default.
- W92013284 magId "92013284" @default.
- W92013284 workType "article" @default.