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• W92086139 abstract "Interstitial cystitis (IC) is an affliction whose etiology and pathogenesis remain obscure, complex, and controversial. It is a disease that typically has a gradual onset with an insidious progression. IC is usually misdiagnosed initially as chronic bacterial cystitis in females or perhaps called urethral syndrome in other cases. In men, it is often confused with either bladder outlet obstruction due to prostate enlargement or prostatitis. As the disease progresses, it is the appearance of pain that is the major impetus to seek medical attention. Pain is the most disabling part of the syndrome and the most difficult for the physician to treat. The impact of IC on the patients' quality of life is significant. The problems in delayed diagnosis may lead to inappropriate suggestions of a psychological etiology rather than a physiological abnormality. No therapy is uniformly successful in IC. There are three basic approaches to treat IC. One utilizes antidepressants, antispasmodics, and antihistamines. A second utilizes cytodestructive techniques including dilation, dimethylsulfoxide, chlorpactin, and silver nitrate. Third, cytoprotective techniques utilize heparin and pentosanpolysulfate. Frequently these therapies must be combined; partial remissions are often achieved with pentosanpolysulfate, heparin, and intravesical dimethylsulfoxide." @default.
• W92086139 created "2016-06-24" @default.
• W92086139 creator A5020056284 @default.
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• W92086139 date "2000-01-01" @default.
• W92086139 modified "2023-09-26" @default.
• W92086139 title "Interstitial Cystitis" @default.
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• W92086139 doi "https://doi.org/10.1016/b978-012288145-9/50101-7" @default.
• W92086139 hasPublicationYear "2000" @default.
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