Matches in SemOpenAlex for { <https://semopenalex.org/work/W92119215> ?p ?o ?g. }
- W92119215 endingPage "737" @default.
- W92119215 startingPage "723" @default.
- W92119215 abstract "This chapter explains how aromatase and hence estrogens play important roles in multiple physiological functions, from the development of genitalia to reproduction, metabolism, brain function and behavior. Aromatase (CYP19) is a member of the cytochrome P450 superfamily. It is found on the endoplasmic reticulum membrane, forming a complex with its co-enzyme/redox partner NADPH–cytochrome P450 reductase. Aromatase is the only known enzyme to catalyze the irreversible and rate-limiting conversion of C19 androgen to form C18 estrogen. Aromatase transcript expression has been detected in rodent and avian brains, especially in the limbic system, hypothalamus, preoptic nucleus, sexually dimorphic nucleus, bed nucleus of the striata terminalis (BNST), hippocampus and cerebellum. Gonadotropins such as luteinizing hormone (LH) and follicle-stimulating hormone (FSH) are usually elevated in aromatase-deficient patients. These aromatase–deficient patients confirmed that estrogen exerts a negative feedback on both the pituitary gland and the hypothalamus to modulate the levels of gonadotropin secreted from the anterior pituitary." @default.
- W92119215 created "2016-06-24" @default.
- W92119215 creator A5048798870 @default.
- W92119215 creator A5062961824 @default.
- W92119215 date "2012-01-01" @default.
- W92119215 modified "2023-10-16" @default.
- W92119215 title "Neuroendocrine Inherited or Induced Aromatase Enzyme Deficits" @default.
- W92119215 cites W1483986092 @default.
- W92119215 cites W1525724332 @default.
- W92119215 cites W1545293228 @default.
- W92119215 cites W1547137876 @default.
- W92119215 cites W1794064462 @default.
- W92119215 cites W1827138247 @default.
- W92119215 cites W1904569017 @default.
- W92119215 cites W19388397 @default.
- W92119215 cites W1965926622 @default.
- W92119215 cites W1969311370 @default.
- W92119215 cites W1969841369 @default.
- W92119215 cites W1970890772 @default.
- W92119215 cites W1971257654 @default.
- W92119215 cites W1971692687 @default.
- W92119215 cites W1972511021 @default.
- W92119215 cites W1975759742 @default.
- W92119215 cites W1979382772 @default.
- W92119215 cites W1980535385 @default.
- W92119215 cites W1984139645 @default.
- W92119215 cites W1985841569 @default.
- W92119215 cites W1988134724 @default.
- W92119215 cites W1995255923 @default.
- W92119215 cites W1998778654 @default.
- W92119215 cites W2001758494 @default.
- W92119215 cites W2002196249 @default.
- W92119215 cites W2003975080 @default.
- W92119215 cites W2004591054 @default.
- W92119215 cites W2007579182 @default.
- W92119215 cites W2009363957 @default.
- W92119215 cites W2010220920 @default.
- W92119215 cites W2010667807 @default.
- W92119215 cites W2011506847 @default.
- W92119215 cites W2012422658 @default.
- W92119215 cites W2015555425 @default.
- W92119215 cites W2015723079 @default.
- W92119215 cites W2017169966 @default.
- W92119215 cites W2020792649 @default.
- W92119215 cites W2022743236 @default.
- W92119215 cites W2025804432 @default.
- W92119215 cites W2026359214 @default.
- W92119215 cites W2029818973 @default.
- W92119215 cites W2030727754 @default.
- W92119215 cites W2032446088 @default.
- W92119215 cites W2033602484 @default.
- W92119215 cites W2038113907 @default.
- W92119215 cites W2041131643 @default.
- W92119215 cites W2041869624 @default.
- W92119215 cites W2043652943 @default.
- W92119215 cites W2044538805 @default.
- W92119215 cites W2045417676 @default.
- W92119215 cites W2048362078 @default.
- W92119215 cites W2049735053 @default.
- W92119215 cites W2050806824 @default.
- W92119215 cites W2054976129 @default.
- W92119215 cites W2055131068 @default.
- W92119215 cites W2056678847 @default.
- W92119215 cites W2062705571 @default.
- W92119215 cites W2063846619 @default.
- W92119215 cites W2064460434 @default.
- W92119215 cites W2065691808 @default.
- W92119215 cites W2066984495 @default.
- W92119215 cites W2067587030 @default.
- W92119215 cites W2070282026 @default.
- W92119215 cites W2077465916 @default.
- W92119215 cites W2078288264 @default.
- W92119215 cites W2087789777 @default.
- W92119215 cites W2093626043 @default.
- W92119215 cites W2095169114 @default.
- W92119215 cites W2097345512 @default.
- W92119215 cites W2103756532 @default.
- W92119215 cites W2104985623 @default.
- W92119215 cites W2106395552 @default.
- W92119215 cites W2118016782 @default.
- W92119215 cites W2120130577 @default.
- W92119215 cites W2121672939 @default.
- W92119215 cites W2127673211 @default.
- W92119215 cites W2128242453 @default.
- W92119215 cites W2141161040 @default.
- W92119215 cites W2142195447 @default.
- W92119215 cites W2146007589 @default.
- W92119215 cites W2147124650 @default.
- W92119215 cites W2147454031 @default.
- W92119215 cites W2150771326 @default.
- W92119215 cites W2162902971 @default.
- W92119215 cites W2171711773 @default.
- W92119215 cites W2324075496 @default.
- W92119215 cites W2728580898 @default.
- W92119215 cites W4230655335 @default.
- W92119215 cites W4239556233 @default.
- W92119215 cites W4242477359 @default.
- W92119215 cites W4247914933 @default.