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- W921549512 abstract "Gr1+ myeloid cells are a patrolling subpopulation of the tumor-infiltrating myeloid cells. Gr1+/c-fms+ myeloid cells (red/green) patrol in tumor vasculature (yellow) in the tumor-stroma border area while c-fms+/dextran+ macrophages (green/yellow) do not migrate in the same area. Gr1+ cells were labeled with Alexa-Fluor-647-conjugated anti-Gr1 antibodies (red), which were coinjected, i.v., with 70 kD rhodamine-conjugated dextran (yellow) in an MMTV-PyMT;ACTB-ECFP;c-fms-EGFP mouse.Dextran first labeled the blood vessels and was taken up by macrophages over time. Shown are the ECFP (blue, mostly epithelial cells), EGFP (green, myeloid cells), rhodamine (yellow, dextran) and Alexa-Fluor-647 (red, Gr1+ antibodies) channels. The movie is shown first with and then without the dextran channel. Time indicates time after injection of antibody and dextran. From Egeblad et al. (2008) Dis. Model. Mech., 1 155-167." @default.
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- W921549512 date "2008-01-01" @default.
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- W921549512 title "Gr1+ myeloid cells are a patrolling subpopulation of the tumor-infiltrating myeloid cells." @default.
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