Matches in SemOpenAlex for { <https://semopenalex.org/work/W9218748> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W9218748 endingPage "236" @default.
- W9218748 startingPage "231" @default.
- W9218748 abstract "Vasogenic cerebral oedema (VCO) was induced in Hooded Wistar rats by intraperitoneal injection of Clostridium perfringens type D epsilon prototoxin. Animals were killed, 1 h to 14 d postinjection, by perfusion fixation under general anaesthesia. VCO was detected by the presence of endogenous albumin in the brain, visualised by immunocytochemistry. As early as 1 h postinjection, albumin was detected in the walls of cerebral microvessels. Maximal diffuse leakage within the neural parenchyma was seen at 24 and 48 h and immunoreactivity was still present at 4 d. At 7 d only few foci were seen, and at 14 d albumin distribution was similar to that in controls. Ultrastructural assessment of the microvessels showed swelling of many astrocytic processes and abnormalities of the endothelial cells varying from swelling with loss of cytoplasmic organelles to cells showing increased electron density. Immunostaining for the endothelial barrier antigen (EBA) showed strongly immunoreactive vessels throughout normal brains. Experimental animals showed partial reduction in EBA expression, most evident at 24 and 48 h, with gradual recovery to normal by 14 d. The exact role that EBA plays in the intact BBB remains obscure." @default.
- W9218748 created "2016-06-24" @default.
- W9218748 creator A5015405111 @default.
- W9218748 creator A5027887430 @default.
- W9218748 creator A5038498656 @default.
- W9218748 creator A5041282900 @default.
- W9218748 creator A5049888563 @default.
- W9218748 creator A5084689064 @default.
- W9218748 date "2000-01-01" @default.
- W9218748 modified "2023-09-28" @default.
- W9218748 title "Toxin-Induced Vasogenic Cerebral Oedema in a Rat Model" @default.
- W9218748 cites W1505601017 @default.
- W9218748 cites W1984482321 @default.
- W9218748 cites W1984685689 @default.
- W9218748 cites W2001437044 @default.
- W9218748 cites W2003717036 @default.
- W9218748 cites W2010622843 @default.
- W9218748 cites W2015475838 @default.
- W9218748 cites W2062496966 @default.
- W9218748 cites W2089589890 @default.
- W9218748 cites W90001822 @default.
- W9218748 doi "https://doi.org/10.1007/978-3-7091-6346-7_47" @default.
- W9218748 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11450014" @default.
- W9218748 hasPublicationYear "2000" @default.
- W9218748 type Work @default.
- W9218748 sameAs 9218748 @default.
- W9218748 citedByCount "7" @default.
- W9218748 countsByYear W92187482015 @default.
- W9218748 countsByYear W92187482017 @default.
- W9218748 countsByYear W92187482020 @default.
- W9218748 countsByYear W92187482022 @default.
- W9218748 countsByYear W92187482023 @default.
- W9218748 crossrefType "book-chapter" @default.
- W9218748 hasAuthorship W9218748A5015405111 @default.
- W9218748 hasAuthorship W9218748A5027887430 @default.
- W9218748 hasAuthorship W9218748A5038498656 @default.
- W9218748 hasAuthorship W9218748A5041282900 @default.
- W9218748 hasAuthorship W9218748A5049888563 @default.
- W9218748 hasAuthorship W9218748A5084689064 @default.
- W9218748 hasConcept C126322002 @default.
- W9218748 hasConcept C134018914 @default.
- W9218748 hasConcept C142724271 @default.
- W9218748 hasConcept C146957229 @default.
- W9218748 hasConcept C196822366 @default.
- W9218748 hasConcept C204232928 @default.
- W9218748 hasConcept C2776125364 @default.
- W9218748 hasConcept C2778402981 @default.
- W9218748 hasConcept C35866371 @default.
- W9218748 hasConcept C4224716 @default.
- W9218748 hasConcept C529278444 @default.
- W9218748 hasConcept C71924100 @default.
- W9218748 hasConceptScore W9218748C126322002 @default.
- W9218748 hasConceptScore W9218748C134018914 @default.
- W9218748 hasConceptScore W9218748C142724271 @default.
- W9218748 hasConceptScore W9218748C146957229 @default.
- W9218748 hasConceptScore W9218748C196822366 @default.
- W9218748 hasConceptScore W9218748C204232928 @default.
- W9218748 hasConceptScore W9218748C2776125364 @default.
- W9218748 hasConceptScore W9218748C2778402981 @default.
- W9218748 hasConceptScore W9218748C35866371 @default.
- W9218748 hasConceptScore W9218748C4224716 @default.
- W9218748 hasConceptScore W9218748C529278444 @default.
- W9218748 hasConceptScore W9218748C71924100 @default.
- W9218748 hasLocation W92187481 @default.
- W9218748 hasLocation W92187482 @default.
- W9218748 hasOpenAccess W9218748 @default.
- W9218748 hasPrimaryLocation W92187481 @default.
- W9218748 hasRelatedWork W1543571891 @default.
- W9218748 hasRelatedWork W1682345769 @default.
- W9218748 hasRelatedWork W1969209049 @default.
- W9218748 hasRelatedWork W1972173644 @default.
- W9218748 hasRelatedWork W2001437044 @default.
- W9218748 hasRelatedWork W2003717036 @default.
- W9218748 hasRelatedWork W2012593448 @default.
- W9218748 hasRelatedWork W2022807001 @default.
- W9218748 hasRelatedWork W2034742219 @default.
- W9218748 hasRelatedWork W2039401375 @default.
- W9218748 hasRelatedWork W2051365194 @default.
- W9218748 hasRelatedWork W2062840925 @default.
- W9218748 hasRelatedWork W2083153124 @default.
- W9218748 hasRelatedWork W2084369099 @default.
- W9218748 hasRelatedWork W2101700662 @default.
- W9218748 hasRelatedWork W2101716445 @default.
- W9218748 hasRelatedWork W2118622987 @default.
- W9218748 hasRelatedWork W2140332419 @default.
- W9218748 hasRelatedWork W2140731474 @default.
- W9218748 hasRelatedWork W2159528099 @default.
- W9218748 isParatext "false" @default.
- W9218748 isRetracted "false" @default.
- W9218748 magId "9218748" @default.
- W9218748 workType "book-chapter" @default.