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- W9226340 abstract "Review is devoted to the place of β-adrenoblockers in the treatment of cardiovascular disease (CVD) in patients with chronic obstructive pulmonary disease (COPD). Currently, it is expedient to use cardioselective -adrenoblockers, such as bisoprolol, metoprolol succinate, carvedilol and nebivolol for the treatment of patients with CVD and COPD. Bisoprolol has the greatest (of all the cardioselective β-adrenoblockers) evidence base of data on the efficacy and safety of using in patients with COPD and CVD. While using a cardioselective β-adrenoblockers external respiration function (ERF) should be controlled. When clinical signs of worsening airway conductance appear, and adverse effects on ERF parameters are observed, β-adrenoblockers dosage should be reduced, while maintaining lower respiratory functions need to be canceled. In general, the use of cardioselective β-adrenoblockers in patients with CVD and COPD is safe, and the benefits of the drugs in this group exceed the risks of exacerbation of COPD. If possible the use of 2-agonists should be limited in patients with CVD in the treatment of COPD because of their negative impact on the cardiovascular system - the preferred use of anticholinergic drugs." @default.
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- W9226340 date "2012-01-01" @default.
- W9226340 modified "2023-09-23" @default.
- W9226340 title "[The place of β-adrenoblockers in the treatment of cardiovascular disease in patients with chronic obstructive pulmonary disease]." @default.
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