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- W923153342 abstract "Publisher Summary This chapter discusses the physiological basis by which the calcium-regulating hormones are affected by the aging process; it also discusses common medical implications related to these hormones and the most advisable therapeutic management of these conditions. Aging is a physiological process affecting the total body, and specifically every cell, organ, and system. For instance, renal function declines with age and renal impairment is a well-recognized cause of calcium malabsorption and bone disease due to the impaired production of the renal metabolites of vitamin D (1,25- dihydroxyvitamin D and 24,25-dihydroxyvitamin D). This process is also accompanied by changes in parathyroid hormone (PTH), calcitonin, and oestrogens and mainly affects the bone. The interrelationship between the aging kidney and the aging parathyroid gland is unique because the latter is an independent one not regulated by other trophic (brain) endocrine factors, and its direct major target organ is the kidney itself. There is no evidence to indicate that primary age-related changes in the parathyroid gland per se cause the increased serum levels of PTH usually observed in the elderly." @default.
- W923153342 created "2016-06-24" @default.
- W923153342 creator A5001152646 @default.
- W923153342 creator A5014652954 @default.
- W923153342 creator A5035943988 @default.
- W923153342 date "1987-01-01" @default.
- W923153342 modified "2023-09-27" @default.
- W923153342 title "The aging kidney and calcium-regulating hormones: vitamin D metabolites, parathyroid hormone and calcitonin" @default.
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