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- W92780360 abstract "Early clinical investigations in oncology are distinct from therapeutics evaluations in other medical disciplines. First, the risks associated with medicines for oncologic diseases dictate that they be evaluated in cancer patients only, and not in healthy volunteers. Second, dose-response relationships are essential to the understanding of potential therapeutic benefit and toxic side effects. Third, determining the specificity of therapeutic value for subsets of patients is essential to the development of effective therapies. For these reasons, a rational system of evaluation has been constructed to optimize the selection of tolerable and effective therapies for comparison with standard treatments in subsequent clinical trials." @default.
- W92780360 created "2016-06-24" @default.
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- W92780360 date "2004-01-01" @default.
- W92780360 modified "2023-09-28" @default.
- W92780360 title "Phase II Trials" @default.
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- W92780360 doi "https://doi.org/10.1007/978-1-59259-739-0_18" @default.
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