Matches in SemOpenAlex for { <https://semopenalex.org/work/W930263329> ?p ?o ?g. }
- W930263329 endingPage "158" @default.
- W930263329 startingPage "121" @default.
- W930263329 abstract "The past decade has seen increasing use of the patch-clamp technique on neutrophils and eosinophils. The main goal of these electrophysiological studies has been to elucidate the mechanisms underlying the phagocyte respiratory burst. NADPH oxidase activity, which defines the respiratory burst in granulocytes, is electrogenic because electrons from NADPH are transported across the cell membrane, where they reduce oxygen to form superoxide anion (O2 −). This passage of electrons comprises an electrical current that would rapidly depolarize the membrane if the charge movement were not balanced by proton efflux. The patch-clamp technique enables simultaneous recording of NADPH oxidase-generated electron current and H+ flux through the closely related H+ channel. Increasing evidence suggests that other ion channels may play crucial roles in degranulation, phagocytosis, and chemotaxis, highlighting the importance of electrophysiological studies to advance knowledge of granulocyte function. Several configurations of the patch-clamp technique exist. Each has advantages and limitations that are discussed here. Meaningful measurements of ion channels cannot be achieved without an understanding of their fundamental properties. We describe the types of measurements that are necessary to characterize a particular ion channel." @default.
- W930263329 created "2016-06-24" @default.
- W930263329 creator A5016708890 @default.
- W930263329 creator A5034320490 @default.
- W930263329 date "2014-01-01" @default.
- W930263329 modified "2023-10-14" @default.
- W930263329 title "Analysis of Electrophysiological Properties and Responses of Neutrophils" @default.
- W930263329 cites W1501202339 @default.
- W930263329 cites W1540307815 @default.
- W930263329 cites W1555733423 @default.
- W930263329 cites W1561818412 @default.
- W930263329 cites W1574274689 @default.
- W930263329 cites W1575402369 @default.
- W930263329 cites W1586099293 @default.
- W930263329 cites W1639029418 @default.
- W930263329 cites W1965401492 @default.
- W930263329 cites W1968492024 @default.
- W930263329 cites W1971120855 @default.
- W930263329 cites W1973472018 @default.
- W930263329 cites W1975439918 @default.
- W930263329 cites W1977695151 @default.
- W930263329 cites W1978887381 @default.
- W930263329 cites W1983011177 @default.
- W930263329 cites W1984746596 @default.
- W930263329 cites W1992539915 @default.
- W930263329 cites W2000129051 @default.
- W930263329 cites W2001574389 @default.
- W930263329 cites W2002251481 @default.
- W930263329 cites W2002580266 @default.
- W930263329 cites W2004933597 @default.
- W930263329 cites W2006404213 @default.
- W930263329 cites W2006698113 @default.
- W930263329 cites W2008002200 @default.
- W930263329 cites W2009667219 @default.
- W930263329 cites W2010490492 @default.
- W930263329 cites W2011424443 @default.
- W930263329 cites W2012428367 @default.
- W930263329 cites W2013296552 @default.
- W930263329 cites W2019431016 @default.
- W930263329 cites W2019588729 @default.
- W930263329 cites W2019998982 @default.
- W930263329 cites W2020439865 @default.
- W930263329 cites W2020760960 @default.
- W930263329 cites W2024062901 @default.
- W930263329 cites W2030441400 @default.
- W930263329 cites W2033387624 @default.
- W930263329 cites W2034548468 @default.
- W930263329 cites W2036970288 @default.
- W930263329 cites W2044936046 @default.
- W930263329 cites W2052790328 @default.
- W930263329 cites W2061830662 @default.
- W930263329 cites W2068032188 @default.
- W930263329 cites W2068406497 @default.
- W930263329 cites W2068968931 @default.
- W930263329 cites W2072438434 @default.
- W930263329 cites W2073653273 @default.
- W930263329 cites W2076882136 @default.
- W930263329 cites W2077717093 @default.
- W930263329 cites W2082304034 @default.
- W930263329 cites W2083963379 @default.
- W930263329 cites W2085669875 @default.
- W930263329 cites W2090401779 @default.
- W930263329 cites W2097400197 @default.
- W930263329 cites W2100092871 @default.
- W930263329 cites W2106413851 @default.
- W930263329 cites W2127265674 @default.
- W930263329 cites W2128149653 @default.
- W930263329 cites W2128876424 @default.
- W930263329 cites W2129853534 @default.
- W930263329 cites W2131137311 @default.
- W930263329 cites W2131836341 @default.
- W930263329 cites W2135563946 @default.
- W930263329 cites W2137108253 @default.
- W930263329 cites W2137760362 @default.
- W930263329 cites W2139056451 @default.
- W930263329 cites W2139215655 @default.
- W930263329 cites W2139852381 @default.
- W930263329 cites W2141648139 @default.
- W930263329 cites W2145100019 @default.
- W930263329 cites W2147142035 @default.
- W930263329 cites W2161344641 @default.
- W930263329 cites W2165682946 @default.
- W930263329 cites W2167684488 @default.
- W930263329 cites W2169473716 @default.
- W930263329 cites W2171313303 @default.
- W930263329 cites W2194981235 @default.
- W930263329 cites W2230389079 @default.
- W930263329 cites W2254869068 @default.
- W930263329 cites W2400711314 @default.
- W930263329 cites W2411636689 @default.
- W930263329 cites W4232766746 @default.
- W930263329 cites W4239384864 @default.
- W930263329 doi "https://doi.org/10.1007/978-1-62703-845-4_9" @default.
- W930263329 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3981097" @default.
- W930263329 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24504950" @default.
- W930263329 hasPublicationYear "2014" @default.
- W930263329 type Work @default.
- W930263329 sameAs 930263329 @default.