Matches in SemOpenAlex for { <https://semopenalex.org/work/W931076965> ?p ?o ?g. }
- W931076965 endingPage "18" @default.
- W931076965 startingPage "10" @default.
- W931076965 abstract "MAGEA10, a cancer/testis antigens expressed in tumors but not in normal tissues with the exception of testis and placenta, represents an attractive target for cancer immunotherapy. However, suppressive cytoenvironment and requirement of specific HLA-alleles presentation frequently led to immunotherapy failure. In this study MAGEA10 was scarcely expressed in cancer patients, but enhanced by viili polysaccharides, which indicates a possibility of increasing epitopes presentation. Furthermore the correlation of gene expression with methylation, indicated by R(2) value for MAGEA10 that was 3 times higher than the value for other MAGE genes tested, provides an explanation of why MAGEA10 was highly inhibited, this is also seen by Kaplan-Meier analysis because MAGEA10 did not change the patients' lifespan. By using Molecular-Docking method, 3 MAGEA10 peptides were found binding to the groove position of HLA-A(∗)0210 as same as MAGEA4 peptide co-crystallized with HLA-A(∗)0210, which indicates that they could be promising for HLA-A(∗)0201 presentation in immunotherapy." @default.
- W931076965 created "2016-06-24" @default.
- W931076965 creator A5010848347 @default.
- W931076965 creator A5013603159 @default.
- W931076965 creator A5013852704 @default.
- W931076965 creator A5021881781 @default.
- W931076965 creator A5025775183 @default.
- W931076965 creator A5032664810 @default.
- W931076965 creator A5041539748 @default.
- W931076965 creator A5049427534 @default.
- W931076965 creator A5068845468 @default.
- W931076965 creator A5069781603 @default.
- W931076965 creator A5083064994 @default.
- W931076965 date "2015-09-01" @default.
- W931076965 modified "2023-10-16" @default.
- W931076965 title "MAGEA10 gene expression in non-small cell lung cancer and A549 cells, and the affinity of epitopes with the complex of HLA-A∗0201 alleles" @default.
- W931076965 cites W1502785776 @default.
- W931076965 cites W1557110892 @default.
- W931076965 cites W1604392326 @default.
- W931076965 cites W1607931568 @default.
- W931076965 cites W1655860314 @default.
- W931076965 cites W1924717348 @default.
- W931076965 cites W1944166248 @default.
- W931076965 cites W1961598420 @default.
- W931076965 cites W1973082806 @default.
- W931076965 cites W1974579112 @default.
- W931076965 cites W1980374511 @default.
- W931076965 cites W2000328927 @default.
- W931076965 cites W2001037936 @default.
- W931076965 cites W2007993961 @default.
- W931076965 cites W2011610339 @default.
- W931076965 cites W2014737696 @default.
- W931076965 cites W2031185632 @default.
- W931076965 cites W2034385827 @default.
- W931076965 cites W2036708294 @default.
- W931076965 cites W2038346203 @default.
- W931076965 cites W2041696131 @default.
- W931076965 cites W2045884759 @default.
- W931076965 cites W2047038388 @default.
- W931076965 cites W2047847470 @default.
- W931076965 cites W2048867608 @default.
- W931076965 cites W2053713206 @default.
- W931076965 cites W2065283382 @default.
- W931076965 cites W2066060190 @default.
- W931076965 cites W2071043125 @default.
- W931076965 cites W2071285517 @default.
- W931076965 cites W2073057620 @default.
- W931076965 cites W2094541817 @default.
- W931076965 cites W2102092419 @default.
- W931076965 cites W2108728444 @default.
- W931076965 cites W2114520383 @default.
- W931076965 cites W2131879910 @default.
- W931076965 cites W2140527988 @default.
- W931076965 cites W2146040535 @default.
- W931076965 cites W2150480196 @default.
- W931076965 cites W2151399556 @default.
- W931076965 cites W2153250619 @default.
- W931076965 doi "https://doi.org/10.1016/j.cellimm.2015.05.004" @default.
- W931076965 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26058806" @default.
- W931076965 hasPublicationYear "2015" @default.
- W931076965 type Work @default.
- W931076965 sameAs 931076965 @default.
- W931076965 citedByCount "3" @default.
- W931076965 countsByYear W9310769652018 @default.
- W931076965 countsByYear W9310769652019 @default.
- W931076965 countsByYear W9310769652021 @default.
- W931076965 crossrefType "journal-article" @default.
- W931076965 hasAuthorship W931076965A5010848347 @default.
- W931076965 hasAuthorship W931076965A5013603159 @default.
- W931076965 hasAuthorship W931076965A5013852704 @default.
- W931076965 hasAuthorship W931076965A5021881781 @default.
- W931076965 hasAuthorship W931076965A5025775183 @default.
- W931076965 hasAuthorship W931076965A5032664810 @default.
- W931076965 hasAuthorship W931076965A5041539748 @default.
- W931076965 hasAuthorship W931076965A5049427534 @default.
- W931076965 hasAuthorship W931076965A5068845468 @default.
- W931076965 hasAuthorship W931076965A5069781603 @default.
- W931076965 hasAuthorship W931076965A5083064994 @default.
- W931076965 hasConcept C104317684 @default.
- W931076965 hasConcept C121608353 @default.
- W931076965 hasConcept C126322002 @default.
- W931076965 hasConcept C147483822 @default.
- W931076965 hasConcept C153911025 @default.
- W931076965 hasConcept C180754005 @default.
- W931076965 hasConcept C188280979 @default.
- W931076965 hasConcept C195616568 @default.
- W931076965 hasConcept C203014093 @default.
- W931076965 hasConcept C2776090121 @default.
- W931076965 hasConcept C2776256026 @default.
- W931076965 hasConcept C2777701055 @default.
- W931076965 hasConcept C2780674031 @default.
- W931076965 hasConcept C502942594 @default.
- W931076965 hasConcept C54355233 @default.
- W931076965 hasConcept C71924100 @default.
- W931076965 hasConcept C83464605 @default.
- W931076965 hasConcept C86803240 @default.
- W931076965 hasConcept C8891405 @default.
- W931076965 hasConceptScore W931076965C104317684 @default.