FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W93245775> ?p ?o ?g. }

• W93245775 endingPage "102" @default.
• W93245775 startingPage "97" @default.
• W93245775 abstract "Calpastatin, the inhibitor protein acting specifically on calpain (EC 3.4.22.17; Ca2+-dependent cysteine proteinase), is known to be widely distributed in mammalian and avian cells. Two different molecular species of calpastatin were isolated and purified to homogeneity from pig heart muscle and from pig erythrocytes, and shown to be of 107 kDa and 68 kDa respectively on SDS/polyacrylamide-gel electrophoresis. Both calpastatins had very similar amino acid compositions when expressed as mol per cent of the residues, differed by only 0.1 pH unit in their isoelectric points, and showed immunological cross-reactivity. One molecule of the 107 kDa species could bind approx. 8 calpain molecules, whereas the 68 kDa inhibitor could bind approx. 5 calpain molecules. These findings suggest similar protein structures of the 107 kDa and 68 kDa calpastatins, each being composed of extended multidomains, with unit inhibitor domains aligned along the polypeptide chain of the molecule. The present study does not conclude, however, whether or not the 68 kDa calpastatin found in erythrocytes is a derived product from the 107 kDa species, which is present as such in heart muscle." @default.
• W93245775 created "2016-06-24" @default.
• W93245775 creator A5027786827 @default.
• W93245775 creator A5030939166 @default.
• W93245775 creator A5041726256 @default.
• W93245775 creator A5067830505 @default.
• W93245775 creator A5077276897 @default.
• W93245775 date "1986-04-01" @default.
• W93245775 modified "2023-09-25" @default.
• W93245775 title "Two different molecular species of pig calpastatin. Structural and functional relationship between 107 kDa and 68 kDa molecules" @default.
• W93245775 cites W1513454707 @default.
• W93245775 cites W1523373796 @default.
• W93245775 cites W1697558679 @default.
• W93245775 cites W1775749144 @default.
• W93245775 cites W1887446700 @default.
• W93245775 cites W1890094243 @default.
• W93245775 cites W1972234658 @default.
• W93245775 cites W1985048506 @default.
• W93245775 cites W1991764697 @default.
• W93245775 cites W1998365181 @default.
• W93245775 cites W2013080645 @default.
• W93245775 cites W2018289835 @default.
• W93245775 cites W2026562182 @default.
• W93245775 cites W2055073050 @default.
• W93245775 cites W2055800890 @default.
• W93245775 cites W2077933682 @default.
• W93245775 cites W2087062084 @default.
• W93245775 cites W2100837269 @default.
• W93245775 cites W2101108802 @default.
• W93245775 cites W2125881320 @default.
• W93245775 cites W2415776498 @default.
• W93245775 cites W2418788417 @default.
• W93245775 cites W983696149 @default.
• W93245775 cites W2411681617 @default.
• W93245775 doi "https://doi.org/10.1042/bj2350097" @default.
• W93245775 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1146654" @default.
• W93245775 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3755595" @default.
• W93245775 hasPublicationYear "1986" @default.
• W93245775 type Work @default.
• W93245775 sameAs 93245775 @default.
• W93245775 citedByCount "57" @default.
• W93245775 countsByYear W932457752012 @default.
• W93245775 countsByYear W932457752014 @default.
• W93245775 countsByYear W932457752022 @default.
• W93245775 crossrefType "journal-article" @default.
• W93245775 hasAuthorship W93245775A5027786827 @default.
• W93245775 hasAuthorship W93245775A5030939166 @default.
• W93245775 hasAuthorship W93245775A5041726256 @default.
• W93245775 hasAuthorship W93245775A5067830505 @default.
• W93245775 hasAuthorship W93245775A5077276897 @default.
• W93245775 hasBestOaLocation W932457752 @default.
• W93245775 hasConcept C101660505 @default.
• W93245775 hasConcept C116084860 @default.
• W93245775 hasConcept C153911025 @default.
• W93245775 hasConcept C181199279 @default.
• W93245775 hasConcept C185592680 @default.
• W93245775 hasConcept C2777488010 @default.
• W93245775 hasConcept C2779201268 @default.
• W93245775 hasConcept C50476208 @default.
• W93245775 hasConcept C55493867 @default.
• W93245775 hasConcept C56928146 @default.
• W93245775 hasConcept C58121356 @default.
• W93245775 hasConcept C86803240 @default.
• W93245775 hasConcept C96294017 @default.
• W93245775 hasConceptScore W93245775C101660505 @default.
• W93245775 hasConceptScore W93245775C116084860 @default.
• W93245775 hasConceptScore W93245775C153911025 @default.
• W93245775 hasConceptScore W93245775C181199279 @default.
• W93245775 hasConceptScore W93245775C185592680 @default.
• W93245775 hasConceptScore W93245775C2777488010 @default.
• W93245775 hasConceptScore W93245775C2779201268 @default.
• W93245775 hasConceptScore W93245775C50476208 @default.
• W93245775 hasConceptScore W93245775C55493867 @default.
• W93245775 hasConceptScore W93245775C56928146 @default.
• W93245775 hasConceptScore W93245775C58121356 @default.
• W93245775 hasConceptScore W93245775C86803240 @default.
• W93245775 hasConceptScore W93245775C96294017 @default.
• W93245775 hasIssue "1" @default.
• W93245775 hasLocation W932457751 @default.
• W93245775 hasLocation W932457752 @default.
• W93245775 hasLocation W932457753 @default.
• W93245775 hasLocation W932457754 @default.
• W93245775 hasOpenAccess W93245775 @default.
• W93245775 hasPrimaryLocation W932457751 @default.
• W93245775 hasRelatedWork W1978116681 @default.
• W93245775 hasRelatedWork W1987262605 @default.
• W93245775 hasRelatedWork W2028321252 @default.
• W93245775 hasRelatedWork W2033749400 @default.
• W93245775 hasRelatedWork W2036482926 @default.
• W93245775 hasRelatedWork W2078366744 @default.
• W93245775 hasRelatedWork W2163784915 @default.
• W93245775 hasRelatedWork W2167866442 @default.
• W93245775 hasRelatedWork W2342236474 @default.
• W93245775 hasRelatedWork W93245775 @default.
• W93245775 hasVolume "235" @default.
• W93245775 isParatext "false" @default.
• W93245775 isRetracted "false" @default.
• W93245775 magId "93245775" @default.

• next