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- W932696032 abstract "随着纳米材料的广泛应用，越来越多的人开始关注并研究纳米材料的环境安全性，特别是生物毒性。基因mRNA受环境的影响往往早于毒性损伤，可作为组织损伤的前兆。以斑马鱼为受试生物，运用RT—PCR研究了ZnO纳米颗粒（5．6mg／L）对肝组织mdrl（多药耐药性基因）、nka（Na^＋-K^＋-ATP酶基因）、ctrl（高亲和铜转运蛋白基因）、hif（低氧诱导因子基因）mRNA的影响，这些基因主要与斑马鱼肝组织自身免疫、细胞膜转运功能以及氧化应激有关。实验发现各基因与对照组相比有显著性差异（P〈0．05），说明ZnO纳米颗粒对斑马鱼肝组织mdrl、nka、ctrl、hif基因有影响。" @default.
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- W932696032 date "2012-01-01" @default.
- W932696032 modified "2023-09-23" @default.
- W932696032 title "纳米ZnO对斑马鱼(Danio rerio)肝组织mdr1、nka、ctr1、hif基因mRNA的影响" @default.
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