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- W93371730 abstract "Comparison of the receptor binding characteristics of rat brain, bovine striatum and adrenal medulla, guinea-pig ileum and mouse vas deferens revealed strong similarities between these tissues. Each contained high affinity D-ala2-D-leu5 -enkephalin (DADLE) and 3H-dihydromorphine (DHM) binding sites which were clearly differentiated by means of competition studies. Detailed analysis of the H-DADLE binding site in guinea-pig ileum suggested that it was similar in nature to that of the mouse vas deferens and brain. In constrast, pharmacological results indicate that enkephalins act on different receptors in the two peripheral tissues. The reason for the discrepancy is as yet unclear." @default.
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- W93371730 date "1980-01-01" @default.
- W93371730 modified "2023-09-27" @default.
- W93371730 title "LIGAND SPECIFICITY OF OPIOID BINDING SITES IN BRAIN AND PERIPHERAL TISSUES" @default.
- W93371730 cites W2032761582 @default.
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- W93371730 doi "https://doi.org/10.1016/b978-0-08-025488-3.50033-7" @default.
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