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- W93432531 abstract "Several published reports have suggested that oral acyclovir can cause renal insufficiency, but baseline renal function was either abnormal or unclear in those reports. We describe a patient with oral acyclovir-induced acute renal failure and a normal serum creatinine level documented just before exposure to the drug. Conceivably, competition with a cephalosporin for renal tubular elimination predisposed our patient to nephrotoxic serum levels of acyclovir. In addition, the patient had sickle cell trait, which might have contributed to a disproportionate degree of hyperkalemia and acidosis seen early in the patient's clinical course." @default.
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- W93432531 date "1999-11-01" @default.
- W93432531 modified "2023-10-04" @default.
- W93432531 title "Acute Renal Insufficiency Due to Oral Acyclovir in a Man With Sickle Cell Trait" @default.
- W93432531 doi "https://doi.org/10.1097/00007611-199911000-00010" @default.
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