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• W93465870 startingPage "223" @default.
• W93465870 abstract "Active infective endocarditis (AIE), which was first described by Osler in 1885 [1], is still a pernicious disease although its clinical course and outcome have changed since the introduction of penicillin and other antibiotics. This made the disease treatable and mortality was dramatically lowered but recent decades have not brought about any further improvement in treatment [2]. Today the mortality rate varies between 15 and 40% [3, 4, 5, 6, 7], which is as high as in patients suffering from acute myocardial infarction complicated by heart failure [8, 9]. However, it should be mentioned that in some published series the surgical mortality is very low. This implies not only that the criteria by which patients are included in studies vary but also that there is something that could be done to improve the outcome of the disease. Because an important percentage of the patients demonstrate a disproportion between the objective state of the disease and their subjective symptoms [10], an improvement in visualization techniques such as magnetic resonance imaging [11] or computed tomography [12] — and especially the proper use of echocardiography [13] — could substantially improve diagnostic procedures. In “surgical cases” such an improvement helps to define the optimal window for surgical intervention and can lead to improved outcome. It is clear that, before the development of modern visualization techniques, root abscess was recognized only during surgery or in postmortem pathological investigations [14]." @default.
• W93465870 created "2016-06-24" @default.
• W93465870 creator A5038267553 @default.
• W93465870 creator A5045879334 @default.
• W93465870 creator A5046343753 @default.
• W93465870 creator A5060641570 @default.
• W93465870 creator A5088568884 @default.
• W93465870 date "2010-01-01" @default.
• W93465870 modified "2023-09-23" @default.
• W93465870 title "Double valve endocarditis and evolving paraannular abscess formation" @default.
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