FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W935013992> ?p ?o ?g. }

• W935013992 abstract "Abstract Background Recent researchers report that vasospasm is caused by that, on one hand, damage of endothelial cells reduces synthesis and liberation of vessel dilator; on the other hand, defluxion of endothelial cells directly exposure vascular smooth muscles in active materials of vasoconstriction in blood. Objective To study whether apoptosis of cerebrovascular cells occurs in symptomatic cerebral vasospasm (CVS) rabbit models by using transmission electron microscope. Design Contrast observation. Settings The Fifth Endemic Area, the 89 Hospital of Chinese PLA; Minimally Invasive Neurosurgical Center, Tangdu Hospital, the Fourth Military Medical University of Chinese PLA. Materials A total of 24 New Zealand rabbits, of either sex, weighing 2.4–3.0 kg, of clear grade, were selected from the Experimental Animal Center of the Fourth Military Medical University of Chinese PLA. JEM-2000EX transmission electron microscope was made in Japan. Methods The experiment was carried out in the Laboratory of Anatomy (National Key Laboratory), the Fourth Military Medical University of Chinese PLA from April 2001 to April 2002. Preparation of symptomatic CVS models: Eighteen animals which were successfully modeled were randomly divided into experimental group ( n = 13) and control group ( n = 5). Animals in the experimental group were poured with blood into cavitas subarachnoidealis; while, animals in the control group were poured with the same volume of saline into cavitas subarachnoidealis. At the 5 th day injection, three rabbits selected from the experimental group were anesthetized and perfused into left ventricle. And then, aorta pectoralis and caval vein were blocked by using ring clamp. Cranium was rapidly cut open to obtain cerebral basilar artery and a few of brain tissues. Both of them were fixed for 8 hours. Two rabbits selected from the control group were perfused with the same method to obtain basilar artery and brain tissues and fix. After fixation by using optic microscope, samples were stained with lead citrate uranyl acetate staining, observed with electron microscope and photographed. Main outcome measures Morphological changes of cytoplasm and nucleus of vascular endothelial cells and smooth muscle cells in the two groups. Results Morphology of vascular endothelial cells in cerebral basilar artery was not changed in the control group. However, vascular endothelial cells in the experimental group showed that cytochondria were swelling; endocytoplasmic reticulum was amplified; chromatin margination was clear; nucleus was in pyknosis; endothelial cells fell down from basal membrane; cell-cell junction was broken. Changes of smooth muscle cells were similar to those of endothelial cells. Severely, it was shown that nuclear pyknosis was obvious, and this was like early apoptosis. Conclusion Apoptosis of endothelial cells may occur in spasmodic vessels." @default.
• W935013992 created "2016-06-24" @default.
• W935013992 creator A5003380444 @default.
• W935013992 creator A5036157316 @default.
• W935013992 creator A5090176604 @default.
• W935013992 date "2007-08-01" @default.
• W935013992 modified "2023-09-26" @default.
• W935013992 title "Apoptosis of endothelial cells of cerebral basilar arteries in symptomatic cerebral vasospasm rabbit modelsElectron microscopic observation" @default.
• W935013992 cites W1963882365 @default.
• W935013992 cites W1975448513 @default.
• W935013992 cites W1983526431 @default.
• W935013992 cites W1984372361 @default.
• W935013992 cites W2012900301 @default.
• W935013992 cites W2014023234 @default.
• W935013992 cites W2017330600 @default.
• W935013992 cites W2018623568 @default.
• W935013992 cites W2019874548 @default.
• W935013992 cites W2032259403 @default.
• W935013992 cites W2035731450 @default.
• W935013992 cites W2056710153 @default.
• W935013992 cites W2061095323 @default.
• W935013992 cites W2074803189 @default.
• W935013992 cites W2089529001 @default.
• W935013992 cites W2109487254 @default.
• W935013992 cites W2148013432 @default.
• W935013992 cites W2154307526 @default.
• W935013992 cites W2380163366 @default.
• W935013992 doi "https://doi.org/10.1016/s1673-5374(07)60094-2" @default.
• W935013992 hasPublicationYear "2007" @default.
• W935013992 type Work @default.
• W935013992 sameAs 935013992 @default.
• W935013992 citedByCount "2" @default.
• W935013992 countsByYear W9350139922018 @default.
• W935013992 crossrefType "journal-article" @default.
• W935013992 hasAuthorship W935013992A5003380444 @default.
• W935013992 hasAuthorship W935013992A5036157316 @default.
• W935013992 hasAuthorship W935013992A5090176604 @default.
• W935013992 hasConcept C105702510 @default.
• W935013992 hasConcept C126322002 @default.
• W935013992 hasConcept C141071460 @default.
• W935013992 hasConcept C171614378 @default.
• W935013992 hasConcept C2776820941 @default.
• W935013992 hasConcept C2777736543 @default.
• W935013992 hasConcept C2778506911 @default.
• W935013992 hasConcept C2781012200 @default.
• W935013992 hasConcept C42219234 @default.
• W935013992 hasConcept C71924100 @default.
• W935013992 hasConceptScore W935013992C105702510 @default.
• W935013992 hasConceptScore W935013992C126322002 @default.
• W935013992 hasConceptScore W935013992C141071460 @default.
• W935013992 hasConceptScore W935013992C171614378 @default.
• W935013992 hasConceptScore W935013992C2776820941 @default.
• W935013992 hasConceptScore W935013992C2777736543 @default.
• W935013992 hasConceptScore W935013992C2778506911 @default.
• W935013992 hasConceptScore W935013992C2781012200 @default.
• W935013992 hasConceptScore W935013992C42219234 @default.
• W935013992 hasConceptScore W935013992C71924100 @default.
• W935013992 hasLocation W9350139921 @default.
• W935013992 hasOpenAccess W935013992 @default.
• W935013992 hasPrimaryLocation W9350139921 @default.
• W935013992 hasRelatedWork W2021506058 @default.
• W935013992 hasRelatedWork W2073890849 @default.
• W935013992 hasRelatedWork W2147342711 @default.
• W935013992 hasRelatedWork W2349009709 @default.
• W935013992 hasRelatedWork W2349146037 @default.
• W935013992 hasRelatedWork W2358987313 @default.
• W935013992 hasRelatedWork W2361770655 @default.
• W935013992 hasRelatedWork W2364102773 @default.
• W935013992 hasRelatedWork W2434713954 @default.
• W935013992 hasRelatedWork W2472960644 @default.
• W935013992 isParatext "false" @default.
• W935013992 isRetracted "false" @default.
• W935013992 magId "935013992" @default.
• W935013992 workType "article" @default.