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- W935070397 abstract "Publisher Summary Marrow transplantation is being increasingly used for the treatment of a variety of diseases, including aplastic anemia, leukemia, and breast cancer. This chapter discusses a series of studies concerning the role of HHV-6 as a pathogen in marrow transplant patients. Human herpesvirus-6 (HHV-6) is a cause of severe interstitial pneumonitis, either directly, or in concert with other respiratory pathogens, in marrow transplants patients. In addition, a series of clinical and experimental observations have implicated HHV-6 marrow infection as an important cause of poor graft function in marrow transplant recipients. Serological and virological evaluation of marrow transplant patients has shown that HHV-6 reactivations are common in seropositive patients after marrow transplantation. Post-transplant HHV-6 primary infections occur and these infections frequently have peripheral and CNS clinical manifestations. This chapter also discusses that HHV-6 is an important pathogen in marrow transplant patients, and the two most common serious clinical manifestations of HHV-6 infection appear to be interstitial pneumonitis and poor marrow function." @default.
- W935070397 created "2016-06-24" @default.
- W935070397 creator A5043378885 @default.
- W935070397 date "1992-01-01" @default.
- W935070397 modified "2023-09-25" @default.
- W935070397 title "Chapter 21 Human herpesvirus-6 and bone marrow transplantation" @default.
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- W935070397 doi "https://doi.org/10.1016/s0168-7069(08)70072-7" @default.
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