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- W93536706 abstract "Abstract Cluster analysis of DNA expression data is a useful tool for identifying biologically relevant gene groupings. It is hence important to apply a rigorous yet intuitive clustering algorithm to uncover these genomic relationships. Here, we describe a clustering framework [1,2] based on a variant of the Generalized Benders Decomposition, the Global Optimum Search [3,4]. We apply the proposed algorithm to experimental DNA microarray data and compare the results to that obtained with some commonly-used algorithms. We also propose an extension to iteratively uncover the optimal biologically coherent structures." @default.
- W93536706 created "2016-06-24" @default.
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- W93536706 date "2007-01-01" @default.
- W93536706 modified "2023-09-24" @default.
- W93536706 title "A novel clustering approach: Global optimum search with enhanced positioning" @default.
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- W93536706 doi "https://doi.org/10.1016/s1570-7946(07)80188-x" @default.
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