Matches in SemOpenAlex for { <https://semopenalex.org/work/W936240143> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W936240143 abstract "Publisher Summary Hyper secretion of endogenous and exogenous growth hormone (GH) can affect all cell systems in the human body. However, beneficial effects on the central nervous system, such as improved cognition, learning capacity, quality of life, or memory are not known. Possible anabolic effects of growth hormone have also been studied in patients with Turner's syndrome who show diminished height and a spectrum of characteristic cognitive disturbances. Long-term GH administration is not associated with abbreviations of these urocognitive deficits nor does long-term growth hormone administration induce improved mental development in patients with Down's syndrome. Furthermore, the chapter discuses treatment approaches for GH-producing tumor. Surgery has been the most commonly chosen first treatment in acromegaly. However, surgery followed by photon irradiation shows significantly lowers quality of life. Other approaches involve somatostatin analogues and genetically engineered GH receptor antagonist pegvisomant or trovert, which inhibits GH action on cells. This GH receptor antagonist is remarkably effective, controlling disease activity and normalizing IGF-I levels in serum in over 90% of patients." @default.
- W936240143 created "2016-06-24" @default.
- W936240143 creator A5049146414 @default.
- W936240143 date "2006-01-01" @default.
- W936240143 modified "2023-09-24" @default.
- W936240143 title "Acromegaly and Brain Function: Effects on the Human Brain during Conditions with Increased Growth Hormone Concentrations" @default.
- W936240143 cites W1496595427 @default.
- W936240143 cites W1584075755 @default.
- W936240143 cites W1980285735 @default.
- W936240143 cites W1980657750 @default.
- W936240143 cites W1988694399 @default.
- W936240143 cites W1989448227 @default.
- W936240143 cites W2022821729 @default.
- W936240143 cites W2028425454 @default.
- W936240143 cites W2028897567 @default.
- W936240143 cites W2034446662 @default.
- W936240143 cites W2049538444 @default.
- W936240143 cites W2076781582 @default.
- W936240143 cites W2079606133 @default.
- W936240143 cites W2080710150 @default.
- W936240143 cites W2120902410 @default.
- W936240143 cites W2126750918 @default.
- W936240143 cites W2147795491 @default.
- W936240143 cites W2153200944 @default.
- W936240143 cites W2153320245 @default.
- W936240143 cites W2407875538 @default.
- W936240143 cites W2464162544 @default.
- W936240143 doi "https://doi.org/10.1016/b978-012088484-1/50023-9" @default.
- W936240143 hasPublicationYear "2006" @default.
- W936240143 type Work @default.
- W936240143 sameAs 936240143 @default.
- W936240143 citedByCount "2" @default.
- W936240143 countsByYear W9362401432012 @default.
- W936240143 crossrefType "book-chapter" @default.
- W936240143 hasAuthorship W936240143A5049146414 @default.
- W936240143 hasConcept C113675107 @default.
- W936240143 hasConcept C126322002 @default.
- W936240143 hasConcept C134018914 @default.
- W936240143 hasConcept C170493617 @default.
- W936240143 hasConcept C2776297358 @default.
- W936240143 hasConcept C2776885963 @default.
- W936240143 hasConcept C2777433750 @default.
- W936240143 hasConcept C2778886798 @default.
- W936240143 hasConcept C2984496839 @default.
- W936240143 hasConcept C71315377 @default.
- W936240143 hasConcept C71924100 @default.
- W936240143 hasConceptScore W936240143C113675107 @default.
- W936240143 hasConceptScore W936240143C126322002 @default.
- W936240143 hasConceptScore W936240143C134018914 @default.
- W936240143 hasConceptScore W936240143C170493617 @default.
- W936240143 hasConceptScore W936240143C2776297358 @default.
- W936240143 hasConceptScore W936240143C2776885963 @default.
- W936240143 hasConceptScore W936240143C2777433750 @default.
- W936240143 hasConceptScore W936240143C2778886798 @default.
- W936240143 hasConceptScore W936240143C2984496839 @default.
- W936240143 hasConceptScore W936240143C71315377 @default.
- W936240143 hasConceptScore W936240143C71924100 @default.
- W936240143 hasLocation W9362401431 @default.
- W936240143 hasOpenAccess W936240143 @default.
- W936240143 hasPrimaryLocation W9362401431 @default.
- W936240143 hasRelatedWork W104820568 @default.
- W936240143 hasRelatedWork W1998786981 @default.
- W936240143 hasRelatedWork W2003945112 @default.
- W936240143 hasRelatedWork W2010594270 @default.
- W936240143 hasRelatedWork W2022154963 @default.
- W936240143 hasRelatedWork W2023730576 @default.
- W936240143 hasRelatedWork W2130558360 @default.
- W936240143 hasRelatedWork W4233275316 @default.
- W936240143 hasRelatedWork W4234009349 @default.
- W936240143 hasRelatedWork W4238046427 @default.
- W936240143 isParatext "false" @default.
- W936240143 isRetracted "false" @default.
- W936240143 magId "936240143" @default.
- W936240143 workType "book-chapter" @default.