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• W936301526 startingPage "8851" @default.
• W936301526 abstract "Proteases and nucleases are enzymes heavily involved in many important biological processes, such as cancer initiation, progression, and metastasis; hence, they are indicative of potential diagnostic biomarkers. Here, we demonstrate a new label free and sensitive electrochemiluminescent (ECL) sensing strategy for protease and nuclease assays that utilize target-triggered desorption of programmable polyelectrolyte films assembled on graphite-like carbon nitride (g-C3N4) film to regulate the diffusion flux of a coreactant. Furthermore, we have built Boolean logic gates OR and AND into the polyelectrolyte films, capable of simultaneously sensing proteases and nucleases in a complicated system by breaking it into simple functions. The developed intelligent permeability controlled enzyme sensor may prove valuable in future medical diagnostics." @default.
• W936301526 created "2016-06-24" @default.
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• W936301526 date "2015-08-11" @default.
• W936301526 modified "2023-09-30" @default.
• W936301526 title "Installing Logic Gates in Permeability Controllable Polyelectrolyte-Carbon Nitride Films for Detecting Proteases and Nucleases" @default.
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• W936301526 doi "https://doi.org/10.1021/acs.analchem.5b01916" @default.
• W936301526 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26228179" @default.
• W936301526 hasPublicationYear "2015" @default.
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