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- W936372656 abstract "Infectious diseases have existed since the dawn of time. The smallpox virus is very large and complex as viruses go and there are numerous related viruses which infect animals and are more or less analogous to the smallpox, the symptoms of which are characterized by the eruption of pimples, blisters, and pustules. The smallpox virus itself can be classified into two distinct types, one of normal virulence (Variola major) and the other an attenuated form (Variola minor). The first symptom observed was the onset of violent shivers or convulsions, followed by a severe rising fever associated with sharp pain, mainly in the lower back. These symptoms lasted for one or two days, the period of invasion. Then the eruptions, associated with a return to normal body temperature, began to occur. Red spots appeared on the face and nose, subsequently extending to the neck, the shoulders, then eventually over the whole body. The spots became pimples and then blisters containing a pale yellow liquid. It was at the beginning of this phase of eruption that one could really gauge the gravity of the infection. At the end of the 18th century inoculation was used relatively frequently in Great Britain but was accompanied by two major inconveniences. There was thus a real need to find a better method of protecting susceptible people from contracting smallpox. The man who put this new method into practice, vaccination, was Edward Jenner." @default.
- W936372656 created "2016-06-24" @default.
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- W936372656 date "2000-01-01" @default.
- W936372656 modified "2023-09-27" @default.
- W936372656 title "On the long struggle of man, before Jenner, to fight smallpox (1721–1798)" @default.
- W936372656 doi "https://doi.org/10.1016/b978-012083475-4/50004-7" @default.
- W936372656 hasPublicationYear "2000" @default.
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