FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W937364103> ?p ?o ?g. }

• W937364103 endingPage "172" @default.
• W937364103 startingPage "167" @default.
• W937364103 abstract "Repetitive magnetic stimulation is a neuropsychiatric and neurorehabilitation tool that can be used to investigate the neurobiology of sensory and motor functions. Few studies have examined the effects of repetitive magnetic stimulation on the modulation of neurotrophic/growth factors and neuronal cells in vitro. Therefore, the current study examined the differential effects of repetitive magnetic stimulation on neuronal cell proliferation as well as various growth factor expression. Immortalized mouse neuroblastoma cells were used as the cell model in this study. Dishes of cultured cells were randomly divided into control, sham, low-frequency (0.5Hz, 1Tesla) and high-frequency (10Hz, 1Tesla) groups (n=4 dishes/group) and were stimulated for 3 days. Expression of neurotrophic/growth factors, Akt and Erk was investigated by Western blotting analysis 3 days after repetitive magnetic stimulation. Neuroblastoma cell proliferation was determined with a cell counting assay. There were differences in cell proliferation based on stimulus frequency. Low-frequency stimulation did not alter proliferation relative to the control, while high-frequency stimulation elevated proliferation relative to the control group. The expression levels of brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), neurotrophin-3 (NT-3) and platelet-derived growth factor (PDGF) were elevated in the high-frequency magnetic stimulation group. Akt and Erk expression was also significantly elevated in the high-frequency stimulation group, while low-frequency stimulation decreased the expression of Akt and Erk compared to the control. In conclusion, we determined that different frequency magnetic stimulation had an influence on neuronal cell proliferation via regulation of Akt and ERK signaling pathways and the expression of growth factors such as BDNF, GDNF, NT-3 and PDGF. These findings represent a promising opportunity to gain insight into how different frequencies of repetitive magnetic stimulation may mediate cell proliferation." @default.
• W937364103 created "2016-06-24" @default.
• W937364103 creator A5002536370 @default.
• W937364103 creator A5032001226 @default.
• W937364103 creator A5069167592 @default.
• W937364103 creator A5073657262 @default.
• W937364103 creator A5078144938 @default.
• W937364103 creator A5084207936 @default.
• W937364103 date "2015-09-01" @default.
• W937364103 modified "2023-09-24" @default.
• W937364103 title "Effects of low- and high-frequency repetitive magnetic stimulation on neuronal cell proliferation and growth factor expression: A preliminary report" @default.
• W937364103 cites W1964821139 @default.
• W937364103 cites W1968623585 @default.
• W937364103 cites W1984621921 @default.
• W937364103 cites W1989032689 @default.
• W937364103 cites W1999522424 @default.
• W937364103 cites W2011860625 @default.
• W937364103 cites W2014493574 @default.
• W937364103 cites W2019216425 @default.
• W937364103 cites W2020518179 @default.
• W937364103 cites W2027411305 @default.
• W937364103 cites W2055594404 @default.
• W937364103 cites W2063841517 @default.
• W937364103 cites W2070003250 @default.
• W937364103 cites W2079472132 @default.
• W937364103 cites W2127009264 @default.
• W937364103 cites W2127715361 @default.
• W937364103 cites W2131866457 @default.
• W937364103 cites W2139565721 @default.
• W937364103 cites W2151169470 @default.
• W937364103 cites W2154009147 @default.
• W937364103 cites W2156092714 @default.
• W937364103 cites W2159516049 @default.
• W937364103 cites W2172152963 @default.
• W937364103 doi "https://doi.org/10.1016/j.neulet.2015.07.038" @default.
• W937364103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26235239" @default.
• W937364103 hasPublicationYear "2015" @default.
• W937364103 type Work @default.
• W937364103 sameAs 937364103 @default.
• W937364103 citedByCount "16" @default.
• W937364103 countsByYear W9373641032016 @default.
• W937364103 countsByYear W9373641032017 @default.
• W937364103 countsByYear W9373641032018 @default.
• W937364103 countsByYear W9373641032019 @default.
• W937364103 countsByYear W9373641032020 @default.
• W937364103 countsByYear W9373641032021 @default.
• W937364103 countsByYear W9373641032022 @default.
• W937364103 crossrefType "journal-article" @default.
• W937364103 hasAuthorship W937364103A5002536370 @default.
• W937364103 hasAuthorship W937364103A5032001226 @default.
• W937364103 hasAuthorship W937364103A5069167592 @default.
• W937364103 hasAuthorship W937364103A5073657262 @default.
• W937364103 hasAuthorship W937364103A5078144938 @default.
• W937364103 hasAuthorship W937364103A5084207936 @default.
• W937364103 hasBestOaLocation W9373641031 @default.
• W937364103 hasConcept C126322002 @default.
• W937364103 hasConcept C134018914 @default.
• W937364103 hasConcept C160539049 @default.
• W937364103 hasConcept C169760540 @default.
• W937364103 hasConcept C170493617 @default.
• W937364103 hasConcept C185856081 @default.
• W937364103 hasConcept C24998067 @default.
• W937364103 hasConcept C2775960820 @default.
• W937364103 hasConcept C2778423431 @default.
• W937364103 hasConcept C2778790584 @default.
• W937364103 hasConcept C54355233 @default.
• W937364103 hasConcept C57074206 @default.
• W937364103 hasConcept C62112901 @default.
• W937364103 hasConcept C62478195 @default.
• W937364103 hasConcept C68710172 @default.
• W937364103 hasConcept C71924100 @default.
• W937364103 hasConcept C75217442 @default.
• W937364103 hasConcept C86803240 @default.
• W937364103 hasConcept C92020748 @default.
• W937364103 hasConcept C95444343 @default.
• W937364103 hasConceptScore W937364103C126322002 @default.
• W937364103 hasConceptScore W937364103C134018914 @default.
• W937364103 hasConceptScore W937364103C160539049 @default.
• W937364103 hasConceptScore W937364103C169760540 @default.
• W937364103 hasConceptScore W937364103C170493617 @default.
• W937364103 hasConceptScore W937364103C185856081 @default.
• W937364103 hasConceptScore W937364103C24998067 @default.
• W937364103 hasConceptScore W937364103C2775960820 @default.
• W937364103 hasConceptScore W937364103C2778423431 @default.
• W937364103 hasConceptScore W937364103C2778790584 @default.
• W937364103 hasConceptScore W937364103C54355233 @default.
• W937364103 hasConceptScore W937364103C57074206 @default.
• W937364103 hasConceptScore W937364103C62112901 @default.
• W937364103 hasConceptScore W937364103C62478195 @default.
• W937364103 hasConceptScore W937364103C68710172 @default.
• W937364103 hasConceptScore W937364103C71924100 @default.
• W937364103 hasConceptScore W937364103C75217442 @default.
• W937364103 hasConceptScore W937364103C86803240 @default.
• W937364103 hasConceptScore W937364103C92020748 @default.
• W937364103 hasConceptScore W937364103C95444343 @default.
• W937364103 hasFunder F4320335295 @default.
• W937364103 hasLocation W9373641031 @default.
• W937364103 hasLocation W9373641032 @default.

• next