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- W937392732 abstract "目的观察塞来昔布对lewis肺癌小鼠血清galectin-3、MMP-9表达的影响。方法C57BL／6小鼠45只随机分为正常对照组、荷瘤对照组和塞来昔布组。荷瘤对照组和塞来昔布组建立lewis肺癌模型。正常对照组和荷瘤对照组给予普通饲料喂养，而塞来昔布组自接种之日起给予含塞来昔布1mg／g的饲料喂养。35天后测量各组皮下肿瘤的重量和肺部肿瘤转移灶的数目。并且使用ELISA检测小鼠血清MMP-9和galectin-3水平。结果塞来昔布组皮下肿瘤重量和肺部肿瘤转移灶数量明显低于荷瘤对照组（P〈0．05）；与荷瘤对照组相比，塞来昔布组血清MMP-9和galectin-3的水平明显降低（P〈0．05）。结论塞来昔布能够抑制lewis肺癌的生长和转移，其机制可能与调节血清galectin-3、MMP-9的表达有关。" @default.
- W937392732 created "2016-06-24" @default.
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- W937392732 date "2012-01-01" @default.
- W937392732 modified "2023-09-23" @default.
- W937392732 title "塞来昔布对小鼠lewis肺癌模型血清galectin-3、MMP-9的影响" @default.
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