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• W93792852 abstract "The isolated activation segment of pig procarboxypeptidase A binds two Tb3+ ions in a strong and specific way. In contrast, the binding of Ca2+, Cd2+ and Mg2+ is weak. The binding of Tb3+ increases the resistance of the isolated activation segment against proteolysis and competes for the binding of the carbocyanine dye Stains-All. This dye forms complexes with the activation segment showing spectral properties similar to those observed with EF-hand structures. The presented results support a previous hypothesis on the existence of two regions in the activation segment of pancreatic procarboxypeptidases structurally related to Ca2+-binding domains of the EF-hand protein family." @default.
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• W93792852 date "1988-05-01" @default.
• W93792852 modified "2023-10-02" @default.
• W93792852 title "Analysis of the conformation and ligand-binding properties of the activation segment of pig procarboxypeptidase A" @default.
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• W93792852 doi "https://doi.org/10.1042/bj2510901" @default.
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