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- W938118832 endingPage "130" @default.
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- W938118832 abstract "Atherosclerosis is a disease of the vascular wall that forms the basis for a large spectrum of pathologies of various organs and tissues. Although massive research efforts in the last decades have yielded valuable information about its underlying molecular mechanisms, this has not led to a translation into effective therapeutic interventions that can stop the progression or even can induce regression of atherosclerosis. This underscores the importance of investigations on the involvement of novel signaling pathways in the development and progression of this condition. In this review we focus on the role of Wnt signaling in atherosclerosis. Experimental evidence is presented that Wnt signaling is involved in many aspects of the development and progression of vascular lesions including endothelial dysfunction, macrophage activation and the proliferation and migration of vascular smooth muscle cells. Subsequently, we will discuss the role of Wnt signaling in myocardial infarction and stroke, two common pathologies resulting from the progression of atherosclerotic lesions towards an unstable phenotype. Despite the fact that the published data sometimes are ambiguous or even conflicting, a picture is emerging that an attenuation of Wnt signaling is beneficial for the cardiovascular system that is compromised by atherosclerosis." @default.
- W938118832 created "2016-06-24" @default.
- W938118832 creator A5012445032 @default.
- W938118832 creator A5086196292 @default.
- W938118832 date "2015-09-01" @default.
- W938118832 modified "2023-10-18" @default.
- W938118832 title "Wnt signaling in atherosclerosis" @default.
- W938118832 cites W1549826613 @default.
- W938118832 cites W1580081728 @default.
- W938118832 cites W1930457864 @default.
- W938118832 cites W1974094726 @default.
- W938118832 cites W1981775580 @default.
- W938118832 cites W1982980295 @default.
- W938118832 cites W1990855183 @default.
- W938118832 cites W1991231767 @default.
- W938118832 cites W1992363536 @default.
- W938118832 cites W2004744099 @default.
- W938118832 cites W2005942794 @default.
- W938118832 cites W2008031660 @default.
- W938118832 cites W2009193373 @default.
- W938118832 cites W2009973913 @default.
- W938118832 cites W2010867414 @default.
- W938118832 cites W2011676273 @default.
- W938118832 cites W2015656201 @default.
- W938118832 cites W2024370562 @default.
- W938118832 cites W2029108949 @default.
- W938118832 cites W2036711492 @default.
- W938118832 cites W2037677443 @default.
- W938118832 cites W2040036705 @default.
- W938118832 cites W2040383667 @default.
- W938118832 cites W2045875104 @default.
- W938118832 cites W2046091099 @default.
- W938118832 cites W2051075947 @default.
- W938118832 cites W2051521659 @default.
- W938118832 cites W2051868320 @default.
- W938118832 cites W2051907575 @default.
- W938118832 cites W2055407404 @default.
- W938118832 cites W2060881606 @default.
- W938118832 cites W2061963189 @default.
- W938118832 cites W2062753790 @default.
- W938118832 cites W2066251900 @default.
- W938118832 cites W2066963386 @default.
- W938118832 cites W2069119449 @default.
- W938118832 cites W2069541735 @default.
- W938118832 cites W2071497196 @default.
- W938118832 cites W2075124840 @default.
- W938118832 cites W2075282559 @default.
- W938118832 cites W2080961942 @default.
- W938118832 cites W2085254971 @default.
- W938118832 cites W2085840119 @default.
- W938118832 cites W2085936371 @default.
- W938118832 cites W2086487946 @default.
- W938118832 cites W2088436698 @default.
- W938118832 cites W2091243251 @default.
- W938118832 cites W2096571949 @default.
- W938118832 cites W2101314557 @default.
- W938118832 cites W2105162447 @default.
- W938118832 cites W2106313387 @default.
- W938118832 cites W2107664383 @default.
- W938118832 cites W2108936410 @default.
- W938118832 cites W2111846279 @default.
- W938118832 cites W2114355635 @default.
- W938118832 cites W2116395753 @default.
- W938118832 cites W2118169228 @default.
- W938118832 cites W2120208856 @default.
- W938118832 cites W2121166230 @default.
- W938118832 cites W2121822802 @default.
- W938118832 cites W2124701846 @default.
- W938118832 cites W2125601956 @default.
- W938118832 cites W2127337667 @default.
- W938118832 cites W2128832316 @default.
- W938118832 cites W2132576204 @default.
- W938118832 cites W2134628583 @default.
- W938118832 cites W2135767680 @default.
- W938118832 cites W2135818002 @default.
- W938118832 cites W2135914580 @default.
- W938118832 cites W2138512695 @default.
- W938118832 cites W2145653235 @default.
- W938118832 cites W2146261185 @default.
- W938118832 cites W2146590089 @default.
- W938118832 cites W2148626940 @default.
- W938118832 cites W2149929597 @default.
- W938118832 cites W2150627565 @default.
- W938118832 cites W2150697906 @default.
- W938118832 cites W2152918946 @default.
- W938118832 cites W2157374802 @default.
- W938118832 cites W2161922223 @default.
- W938118832 cites W2162409663 @default.
- W938118832 cites W2163768568 @default.
- W938118832 cites W2166862263 @default.
- W938118832 cites W2168639224 @default.
- W938118832 cites W2178596412 @default.
- W938118832 cites W2325831736 @default.
- W938118832 cites W4248066024 @default.
- W938118832 doi "https://doi.org/10.1016/j.ejphar.2015.05.023" @default.
- W938118832 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25987418" @default.
- W938118832 hasPublicationYear "2015" @default.
- W938118832 type Work @default.