Matches in SemOpenAlex for { <https://semopenalex.org/work/W93934174> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W93934174 endingPage "7" @default.
- W93934174 startingPage "2142" @default.
- W93934174 abstract "Human artificial chromosomes (HACs) exhibit several potential characteristics desired for an ideal gene delivery vector, including stable episomal maintenance and the capacity to carry large genomic loci with their regulatory elements, thus allowing the physiological regulation of the introduced gene. Stem cells, including hematopoietic stem cells, bone marrow-derived MSCs and iPS cells, can potentially avoid immune rejection due to their being obtained from the patient's own tissues. Recently, we succeeded the complete correction of a genetic deficiency in iPS cells derived from a human Duchenne muscular dystrophy patient using the HAC technology. Therefore, the combination of patient specific stem cells and HAC containing defective genes potentially represents a powerful tool for gene and cell therapies." @default.
- W93934174 created "2016-06-24" @default.
- W93934174 creator A5004986891 @default.
- W93934174 creator A5049283637 @default.
- W93934174 date "2011-12-01" @default.
- W93934174 modified "2023-09-23" @default.
- W93934174 title "[Toward gene and cell therapy using human artificial chromosome]." @default.
- W93934174 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22242311" @default.
- W93934174 hasPublicationYear "2011" @default.
- W93934174 type Work @default.
- W93934174 sameAs 93934174 @default.
- W93934174 citedByCount "0" @default.
- W93934174 crossrefType "journal-article" @default.
- W93934174 hasAuthorship W93934174A5004986891 @default.
- W93934174 hasAuthorship W93934174A5049283637 @default.
- W93934174 hasConcept C104317684 @default.
- W93934174 hasConcept C10854531 @default.
- W93934174 hasConcept C10882517 @default.
- W93934174 hasConcept C109159458 @default.
- W93934174 hasConcept C111599444 @default.
- W93934174 hasConcept C132144397 @default.
- W93934174 hasConcept C135983454 @default.
- W93934174 hasConcept C1491633281 @default.
- W93934174 hasConcept C203014093 @default.
- W93934174 hasConcept C2778943923 @default.
- W93934174 hasConcept C2780007613 @default.
- W93934174 hasConcept C28328180 @default.
- W93934174 hasConcept C30481170 @default.
- W93934174 hasConcept C32470452 @default.
- W93934174 hasConcept C40767141 @default.
- W93934174 hasConcept C43953973 @default.
- W93934174 hasConcept C54355233 @default.
- W93934174 hasConcept C70721500 @default.
- W93934174 hasConcept C86803240 @default.
- W93934174 hasConcept C95444343 @default.
- W93934174 hasConceptScore W93934174C104317684 @default.
- W93934174 hasConceptScore W93934174C10854531 @default.
- W93934174 hasConceptScore W93934174C10882517 @default.
- W93934174 hasConceptScore W93934174C109159458 @default.
- W93934174 hasConceptScore W93934174C111599444 @default.
- W93934174 hasConceptScore W93934174C132144397 @default.
- W93934174 hasConceptScore W93934174C135983454 @default.
- W93934174 hasConceptScore W93934174C1491633281 @default.
- W93934174 hasConceptScore W93934174C203014093 @default.
- W93934174 hasConceptScore W93934174C2778943923 @default.
- W93934174 hasConceptScore W93934174C2780007613 @default.
- W93934174 hasConceptScore W93934174C28328180 @default.
- W93934174 hasConceptScore W93934174C30481170 @default.
- W93934174 hasConceptScore W93934174C32470452 @default.
- W93934174 hasConceptScore W93934174C40767141 @default.
- W93934174 hasConceptScore W93934174C43953973 @default.
- W93934174 hasConceptScore W93934174C54355233 @default.
- W93934174 hasConceptScore W93934174C70721500 @default.
- W93934174 hasConceptScore W93934174C86803240 @default.
- W93934174 hasConceptScore W93934174C95444343 @default.
- W93934174 hasIssue "12" @default.
- W93934174 hasLocation W939341741 @default.
- W93934174 hasOpenAccess W93934174 @default.
- W93934174 hasPrimaryLocation W939341741 @default.
- W93934174 hasRelatedWork W140598396 @default.
- W93934174 hasRelatedWork W1532962884 @default.
- W93934174 hasRelatedWork W1844290320 @default.
- W93934174 hasRelatedWork W2036614178 @default.
- W93934174 hasRelatedWork W2155509066 @default.
- W93934174 hasRelatedWork W2160673389 @default.
- W93934174 hasRelatedWork W2753217443 @default.
- W93934174 hasRelatedWork W3169014305 @default.
- W93934174 hasRelatedWork W74244029 @default.
- W93934174 hasRelatedWork W93934174 @default.
- W93934174 hasVolume "69" @default.
- W93934174 isParatext "false" @default.
- W93934174 isRetracted "false" @default.
- W93934174 magId "93934174" @default.
- W93934174 workType "article" @default.